SynthesisEuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology2021
Cardiovascular mortality and morbidity in patients undergoing percutaneous coronary intervention after out-of-hospital cardiac arrest: a systematic review and meta-analysis.
Synthesis in EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
8 citing papers in PubMed, 11 citations in OpenAlex.
- Impact of Resuscitation Status and Cardiac Arrest Location on Survival and Neurological Outcomes in Acute Coronary Syndrome Patients Undergoing Coronary Angiography.Journal of clinical medicine · 2026Article
- Oral P2YInternational journal of cardiology. Heart & vasculature · 2026Article
- Coronary angiography/revascularization status and 1-year cardiovascular outcomes in survivors of out-of-hospital cardiac arrest.Scientific reports · 2026Article
- Bleeding complications in patients with out-of-hospital cardiac arrest treated with cangrelor and oral P2Y12 inhibitors.European heart journal. Acute cardiovascular care · 2026Article
- Clinical characteristics of patients with cardiogenic shock after out-of-hospital cardiac arrest (OHCA) compared to patients with cardiogenic shock without OHCA.Cardiology journal · 2026Article
- Balancing Bleeding and Thrombosis: A Case of Antiplatelet Bridging with Cangrelor and Hyperfibrinolytic Disseminated Intravascular Coagulation.TH open : companion journal to thrombosis and haemostasis · 2026Article
- Pre-arrest oral anticoagulants' impact on cardiac arrest mortality: MIMIC-IV cohort retrospect.Frontiers in cardiovascular medicine · 2025Article
- Percutaneous Coronary Intervention in Out-of-Hospital Cardiac Arrest Related to Acute Coronary Syndrome: A Literature Review.Journal of clinical medicine · 2023Review
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsThe aim of this meta-analysis was to appraise the burden of cardiovascular mortality and morbidity among patients undergoing percutaneous coronary intervention (PCI) after out-of-hospital cardiac arrest (OHCA). METHODS AND
resultsThis was a meta-analysis of studies assessing the cardiovascular mortality or at least one other pre-defined outcome in OHCA patients undergoing PCI. Forty-nine studies with a total of 301,902 patients (73,634 OHCA and 228,268 non-OHCA patients) were included. Compared to non-OHCA patients, all-cause mortality was higher in OHCA patients (29% vs 4%). The cause of 39% of deaths among OHCA patients was cardiovascular: PCI was more frequently unsuccessful (9.2% vs 7.6%) and there were higher rates of stent thrombosis (2.9% vs 0.8%), myocardial infarction (1.7% vs 1.4%), relevant bleeding (10.2% vs 2.1%) and stroke (1.7% vs 0.5%). OHCA patients compared to non-OHCA patients had a higher risk of all-cause mortality (risk ratio [RR] 6.4, 95% CI: 5.5-7.4), cardiovascular death (4.6, 1.1-19), unsuccessful coronary revascularisation (1.4, 1.1-1.7), stent thrombosis (3.8, 0.6-22.7), myocardial infarction (1.4, 1.1-1.7), relevant bleeding (3.2, 2.5-4.1) and stroke (3.1, 2.3-4.3).
conclusionsAlmost one third of OHCA patients undergoing PCI die and more than one third of the fatalities are attributable to cardiovascular causes. The burden of ischaemic and bleeding complications was consistently higher and the success rates of PCI lower among OHCA as compared to non-OHCA patients.
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