ArticleBMC medicine2020
Effects of a physical activity program from diagnosis on cardiorespiratory fitness in children with cancer: a national non-randomized controlled trial.
Article in BMC medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 26 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Rehabilitation Including Social Activity and Education in Children and Teenagers With Cancer
Rehabilitation Including Social and Education in Children and Teenagers With Cancer
Social and Physical Activity as Rehabilitation for Preschool Kids With Cancer (SPARK)
Who cites it
26 citing papers in PubMed, 5 syntheses or guidelines pooled it, 40 citations in OpenAlex.
- Nutrition and physical activity interventions delivered to children and young people during cancer treatment: a systematic literature review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Pooled it
- Exploring physical activity experiences among children and adolescents during and beyond cancer treatment: a meta-synthesis of qualitative research.BMC cancer · 2026Pooled it
- Supervised Physical Activity Interventions in Children and Adolescents with Cancer Undergoing Treatment-A Systematic Review.Current oncology (Toronto, Ont.) · 2025Pooled it
- Parents' perceptions of physical activity for their children with cancer: a qualitative meta-synthesis.Frontiers in pediatrics · 2025Pooled it
- Physical capacity in children and adolescents with newly diagnosed cancer: A systematic review and meta-analysis.Pediatric blood & cancer · 2024Pooled it
- Gross motor function, functional level, physical performance, and muscle strength in preschool children newly diagnosed with cancer: Data from the RePlay trial.European journal of pediatrics · 2026Trial
- Children with cancer and their cardiorespiratory fitness and physical function-the long-term effects of a physical activity program during treatment: a multicenter non-randomized controlled trial.Journal of cancer survivorship : research and practice · 2025Trial
- Physical activity levels of an inpatient paediatric population: a cross-sectional service evaluation.BMJ paediatrics open · 2026Article
- Multimodal Exercise and Nutritional Interventions in Pediatric Cancer: Effects on Physical Function, Body Composition, and Metabolic Health-A Narrative Review.Children (Basel, Switzerland) · 2026Review
- Incidence, characteristics and suggestions for prevention of adverse events in supervised pediatric oncology exercise sessions.Frontiers in pediatrics · 2026Article
- Interim implementation and effectiveness results from the IMplementation of Physical Activity for Children and adolescents on Treatment (IMPACT) intervention and trial.Frontiers in pediatrics · 2026Article
- Muscle fitness and physical function in children and adolescents with newly diagnosed cancer.Frontiers in pediatrics · 2026Article
- Sarcopenia in children with acute leukemia worsened after induction therapy.Endocrine journal · 2025Article
- Exploring childhood cancer survivor, parent, healthcare and community professionals' experiences of, and priorities for, using digital health to engage in physical activity: a mixed methods study.Journal of cancer survivorship : research and practice · 2025Article
- Exploration of the impact of participation in a multidisciplinary family lifestyle intervention on exercise and diet quality during treatment for childhood cancer: the VIE program.BMC pediatrics · 2025Article
- Identifying causes of balance impairment and exploring sensory contributions to balance in pediatric oncology: A scoping review.Critical reviews in oncology/hematology · 2024Article
- The importance of cardiopulmonary exercise test to improve supportive care in adolescent and young adult survivors of childhood cancer.Pediatric research · 2023Article
- Childhood cancer survivors' and their parents' experiences with participation in a physical and social intervention during cancer treatment: A RESPECT study.Journal of advanced nursing · 2022Article
- Rehabilitation Including Structured Active Play for Preschoolers With Cancer (RePlay)-Study Protocol for a Randomized Controlled Trial.Frontiers in pediatrics · 2022Article
- Promoting positive physical activity behaviors for children and adolescents undergoing acute cancer treatment: Development of the CanMOVE intervention using the Behavior Change Wheel.Frontiers in pediatrics · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 6 institutions in 2 countries.
Funding
Abstract
backgroundChildren with cancer experience impaired cardiorespiratory fitness and physical function during and after treatment restricting their possibilities to engage in social activities including sport, leisure activities, and school. The objectives were to determine the effects of classmate-supported, controlled, supervised, in-hospital, physical activity program to preserve cardiorespiratory fitness and physical function from time of diagnosis in children with cancer.
methodsNational non-randomized controlled trial including schoolchildren aged 6-18 years at diagnosis treated with chemo-/radiotherapy. We included 120 of 128 eligible patients (94%) in the intervention group (62.5% boys, 11.2 ± 3.1 years) from East Denmark and 58 patients in the control group (57% boys, 11.0 ± 3.2 years) from West Denmark. Eight children from the control group withdrew from participation. The groups were comparable in anthropometrics and cancer diagnoses (p > 0.05). The intervention consisted of (i) supervised in-hospital physical activity from diagnosis and throughout intensive treatment, (ii) 90-min general educational session on cancer and therapy in the child's school class, and (iii) selection of two classmates as ambassadors who took turns to support the child's physical training during the daytime. The primary outcome was cardiorespiratory fitness (VO
resultsAmbassadors were identified for all, and 2542 individual and 621 group training sessions were held. VO
conclusionsPeer-supported, supervised, in-hospital, physical activity is safe and feasible in children with cancer during treatment. Further, the results suggest that the intervention might mitigate impairments in cardiorespiratory fitness during treatment in children with cancer.
trial registrationThe study was prospectively registered on the 11 January 2013. Clinicaltrial.gov NCT01772849 and NCT01772862 .
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.