ArticleJournal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing2021
Mid-term feasibility, safety and outcomes of left bundle branch pacing-single center experience.
Article in Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05600699 (Long-term Efficacy and Safety Research of Left Bundle Branch Pacing), which is not on this map. Cited by 16 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Long-term Efficacy and Safety Research of Left Bundle Branch Pacing
Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 30 citations in OpenAlex.
- 2023 HRS/APHRS/LAHRS guideline on cardiac physiologic pacing for the avoidance and mitigation of heart failure.Heart rhythm · 2023Guideline
- The electrocardiogram characteristics and pacing parameters of permanent left bundle branch pacing: a systematic review and meta-analysis.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2022Pooled it
- Left Bundle Branch Area Pacing in Cardiac Resynchronization Therapy: How Does It Compare to Biventricular Pacing in Terms of Electrocardiographic Parameters and Procedural Outcomes?Journal of clinical medicine · 2025Article
- Article
- Current Role of Conduction System Pacing in Patients Requiring Permanent Pacing.Korean circulation journal · 2024Review
- His Bundle Pacing: Predicting Mortality and Major Complications in Mid-Term Follow-Up.Journal of clinical medicine · 2024Article
- 2023 HRS/APHRS/LAHRS guideline on cardiac physiologic pacing for the avoidance and mitigation of heart failure.Journal of arrhythmia · 2023Article
- Early Experience of Patients with left Bundle Branch Block Corrected through Left Bundle Branch Area Pacing Compared with Conventional Right Ventricular Pacing: A Single-Center Retrospective Study.Acta Cardiologica Sinica · 2023Article
- My preferred approach to left bundle branch pacing: Lumenless leads.Heart rhythm O2 · 2023Article
- Left bundle branch pacing: An evolving site for physiological pacing.Journal of arrhythmia · 2021Article
- How to Implant His Bundle and Left Bundle Pacing Leads: Tips and Pearls.Cardiac failure review · 2021Review
- Left bundle branch pacing guided by premature ventricular complexes during implant.HeartRhythm case reports · 2020Article
- Pacing for atrioventricular block with preserved left ventricular function: On-treatment comparison between his bundle, left bundle branch, and right ventricular pacing.Indian pacing and electrophysiology journalArticle
- Assessment of Clinical Outcomes and Electrophysiological Parameters of Left Bundle Branch Area Pacing: A Single-center Prospective Study with 12-month Follow-up.International journal of applied & basic medical researchArticle
- Electroanatomical mapping assisted conduction system pacing.Indian pacing and electrophysiology journalArticle
- Feasibility, safety and outcomes of left bundle branch pacing in octogenarians.Indian heart journalObservational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHis bundle pacing (HBP) has evolved as the most physiological form of pacing but associated with limitations. Recently, left bundle branch pacing (LBBP) is emerging as an effective alternative strategy for HBP.
objectivesOur study was designed to assess the feasibility, efficacy, electrophysiological parameters, and mid-term outcomes of LBBP in Indian population.
methodsAll patients requiring permanent pacemaker implantation for symptomatic bradycardia and heart failure were prospectively enrolled. Echocardiography, QRS duration, pacing parameters, left bundle (LB) potentials, paced QRS duration, and peak left ventricular activation time (pLVAT) were recorded.
resultsLBBP was successful in 93 out of 99 patients (94% acute success). Mean age was 62.6 ± 13 years, male 59%, diabetes 69%, and coronary artery disease 65%. Follow-up duration was 4.8 months (range1-12 months). Indication for pacing included atrioventricular (AV) block 43%, cardiac resynchronization therapy 44%, and AV node ablation 4%. LB potential was noted in 37 patients (40%). QRS duration reduced from 144.38 ± 34.6 at baseline to 110.8 ± 12.4 ms after LBBP (p < 0.0001). Pacing threshold was 0.59 ± 0.22 V and sensed R wave 14.14 ± 7.19 mV, and it remained stable during follow-up. Lead depth in the septum was 9.62 mm. LV ejection fraction increased from 44.96 to 53.3% after LBBP (p < 0.0001). One died due to respiratory tract infection on follow up.
conclusionLBBP is a safe and effective strategy (94% acute success) of physiological pacing. The pacing parameters remained stable over a period of 12 months follow-up. LBBP can effectively overcome the limitations of HBP.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.