Evidence map›Paper›PMID 32623623›Full record

ArticleBiological trace element research2021

Effect of Iodine and Selenium on Proliferation, Viability, and Oxidative Stress in HTR-8/SVneo Placental Cells.

Nahal Habibi, Tanja Jankovic-Karasoulos, Shalem Yiner-Lee Leemaqz, Maxime Francois, Shao Jia Zhou, Wayne R Leifert, Anthony V Perkins, Claire T Roberts, Tina Bianco-Miotto

Abstract read
PubMed Publisher
In one paragraph

Article in Biological trace element research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Oxidative Stress in Pregnancy.Biomolecules · 2023
    Review
  3. Article
  4. Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Nahal HabibiSchool of Agriculture, Food and Wine, Waite Research Institute, University of Adelaide, Adelaide, SA, 5005, Australia.ORCID https://orcid.org/0000-0003-1017-8032
Tanja Jankovic-KarasoulosRobinson Research Institute, University of Adelaide, Adelaide, SA, 5005, Australia.ORCID https://orcid.org/0000-0003-4293-359X
Shalem Yiner-Lee LeemaqzRobinson Research Institute, University of Adelaide, Adelaide, SA, 5005, Australia.ORCID https://orcid.org/0000-0003-4616-8426
Maxime FrancoisCSIRO Health and Biosecurity, Future Science Platforms Probing Biosystems, Adelaide, SA, 5000, Australia.ORCID https://orcid.org/0000-0003-1317-1506
Shao Jia ZhouSchool of Agriculture, Food and Wine, Waite Research Institute, University of Adelaide, Adelaide, SA, 5005, Australia.ORCID https://orcid.org/0000-0003-4012-983X
Wayne R LeifertCSIRO Health and Biosecurity, Future Science Platforms Probing Biosystems, Adelaide, SA, 5000, Australia.ORCID https://orcid.org/0000-0003-0535-7327
Anthony V PerkinsSchool of Medical Science, Griffith University, Gold Coast Campus, Parklands Drive, Southport, QLD, 9726, Australia.ORCID https://orcid.org/0000-0002-9829-6772
Claire T RobertsRobinson Research Institute, University of Adelaide, Adelaide, SA, 5005, Australia.ORCID https://orcid.org/0000-0002-9250-2192
Tina Bianco-MiottoSchool of Agriculture, Food and Wine, Waite Research Institute, University of Adelaide, Adelaide, SA, 5005, Australia. tina.bianco@adelaide.edu.au.ORCID https://orcid.org/0000-0002-8431-5338
The University of Adelaide · AUCSIRO Health and Biosecurity · AUFlinders University · AUGriffith University · AU

Funding

Flinders University Matthew Flinders FellowshipNational Health and Medical Research Council GNT1161079National Health and Medical Research Council GNT1174971
6 · The paper itself

Abstract

Adequate maternal micronutrition is vital for placental formation, fetal growth, and development. Oxidative stress adversely affects placental development and function and an association between deficient placental development, oxidative stress, and micronutrient deficiency has been observed. Selenium and iodine are two essential micronutrients with antioxidant properties. Epidemiological studies have shown that poor micronutrient status in pregnant women is associated with a higher incidence of pregnancy complications. The aim of this study was to determine how selenium, iodine, and their combination impact oxidative stress in placental trophoblast cells. HTR8/SVneo extravillous trophoblasts were supplemented with a concentration range of organic and inorganic selenium, potassium iodide, or their combination for 24 h. Oxidative stress was then induced by treating cells with menadione or H

Indexed as

IodineOxidative StressPlacentaSeleniumCell ProliferationFemaleHumansHydrogen PeroxidePregnancyTrophoblastsHydrogen PeroxideIodineSeleniumIodineLipid peroxidationOxidative stressPlacentaReactive oxygen speciesSelenium

Identifiers

PMID32623623
OpenAlexW3039298885

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.