Evidence map›Paper›PMID 32623149›Full record

ArticleJournal of inorganic biochemistry2020

Investigating the roles of the conserved Cu

Sambuddha Banerjee, Ryan J Garrigues, Mina N Chanakira, Jacob J Negron-Olivo, Yasmene H Odeh, Anne M Spuches, R Martin Roop, Joshua Edison Pitzer, Daniel W Martin, Saumya Dasgupta

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of inorganic biochemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sambuddha BanerjeeDepartment of Chemistry, East Carolina University, Greenville, NC 27858, USA. Electronic address: banerjees17@ecu.edu.
Ryan J GarriguesDepartment of Microbiology and Immunology, Brody School of Medicine, East Carolina University, Greenville, NC 27834, USA.
Mina N ChanakiraDepartment of Chemistry, East Carolina University, Greenville, NC 27858, USA.
Jacob J Negron-OlivoDepartment of Chemistry, East Carolina University, Greenville, NC 27858, USA.
Yasmene H OdehDepartment of Chemistry, East Carolina University, Greenville, NC 27858, USA.
Anne M SpuchesDepartment of Chemistry, East Carolina University, Greenville, NC 27858, USA.
R Martin RoopDepartment of Microbiology and Immunology, Brody School of Medicine, East Carolina University, Greenville, NC 27834, USA.
Joshua Edison PitzerDepartment of Microbiology and Immunology, Brody School of Medicine, East Carolina University, Greenville, NC 27834, USA.
Daniel W MartinDepartment of Microbiology and Immunology, Brody School of Medicine, East Carolina University, Greenville, NC 27834, USA.
Saumya DasguptaDepartment of Chemistry, Amity Institute of Applied Sciences, Amity University Kolkata, WB, 700135, India.

Funding

Manganese transport and virulence in BrucellaR21AI112745 · NIAID · EAST CAROLINA UNIVERSITY · PI ROOP, ROY M · 2014 to 2015
$402k
MucR gene silencing and Brucella virulenceR21AI141438 · NIAID · EAST CAROLINA UNIVERSITY · PI ROOP, ROY M · 2019 to 2020
$401k
NIAID NIH HHS R21 AI112745NIAID NIH HHS R21 AI141438
6 · The paper itself

Abstract

Brucella is a zoonotic pathogen requiring iron for its survival and acquires this metal through the expression of several high-affinity uptake systems. Of these, the newly discovered ferrous iron transporter, FtrABCD, is proposed to take part in ferrous iron uptake. Sequence homology shows that, FtrA, the proposed periplasmic ferrous-binding component, is a P19-type protein (a periplasmic protein from C. jejuni which shows Cu

Indexed as

Bacterial ProteinsBrucellaCation Transport ProteinsCopperManganeseMutagenesis, Site-DirectedMutationPhase TransitionProtein BindingProtein FoldingProtein StabilityProtein Structure, SecondaryBacterial ProteinsCation Transport ProteinsCopperManganeseBrucellaCu(2+)-binding mutantDifferential scanning calorimetryFtrAHomology modelIsothermal titration calorimetry

Identifiers

PMID32623149
PMCPMC7484176

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.