Evidence map›Paper›PMID 32623086›Full record

ArticleInternational journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases2020

Cross-infection of adenovirus among medical staff: A warning from the intensive care unit in a tertiary care teaching hospital in China.

Minhui Dai, Yanhao Wu, Hongyi Tan, Jing Deng, Maodan Hou, Wenzhong Peng, Guo Chen, Yi Li, Haitao Li, Pinhua Pan and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.1field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Minhui DaiRespiratory Department, Xiangya Hospital, Central South University, China.
Yanhao WuRespiratory Department, Xiangya Hospital, Central South University, China.
Hongyi TanCentral Hospital, Changsha, Hunan Province, China.
Jing DengCentral South University Xiangya School of Public Health, China.
Maodan HouRespiratory Department, Xiangya Hospital, Central South University, China.
Wenzhong PengRespiratory Department, Xiangya Hospital, Central South University, China.
Guo ChenRespiratory Department, Xiangya Hospital, Central South University, China.
Yi LiRespiratory Department, Xiangya Hospital, Central South University, China.
Haitao LiCancer Hospital of Hunan Province, China.
Pinhua PanState Key Laboratory of Anti-Infective Drug Development, Dongguan 523871, China; Respiratory Department, Xiangya Hospital, Central South University, China. Electronic address: pinhuapan668@csu.edu.cn.
Jingmei LuRespiratory Department, Xiangya Hospital, Central South University, China. Electronic address: 1711310470@qq.com.
Central South University · CNXiangya Hospital Central South University · CNChangsha Central Hospital · CNHunan Cancer Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

rationaleIn 2019, a small HAdV55-associated outbreak of adenovirus infection occurred among the intensive care unit (ICU) staff in Xiangya Hospital of Central South University in Hunan Province, China, during the treatment of a patient.

objectiveTo investigate the characteristics of a nosocomial adenovirus outbreak in an ICU.

methodsWe evaluated all the patients treated and the medical staff working in the ICU from August 1 to September 4, 2019. We further performed an epidemiological and molecular analysis for this outbreak from patient to healthcare workers and between healthcare workers. After the outbreak, we adopted exposure prevention and droplet prevention measures based on standard precautions. MEASUREMENTS AND MAIN

resultsBetween August 1 and August 27, 2019, 27 cases of human adenovirus cross-infection were reported in our institution. Among the cases, eleven were doctors (41%), eleven were nurses (41%), three were respiratory therapists (11%), and two were caregivers (7%). The attack rate was 28.4%, and the fatality rate was 0. The results showed that contact with the index case, lack of hand hygiene or gloving adherence were risk factors for infection after adenovirus exposure. After taking specific precautions, no new cases of infection have appeared since August 27.

conclusionsOur results show that HAdV55 in a single patient had strong transmission potential in an intensive care unit with adequate facilities and standardized operation. We provide convincing evidence indicating that attention could be highlighted on the role of standard and specific precautions for controlling the spread of adenovirus in ICUs.

Indexed as

Adenoviruses, HumanAdenovirus Infections, HumanAdultChinaCross InfectionFemaleHand HygieneHospitals, TeachingHumansIntensive Care UnitsMaleMedical StaffMiddle AgedPhylogenyTertiary Health CareYoung AdultDisease outbreakEpidemiologyHAdV-55Human adenovirusMedical staff

Identifiers

PMID32623086
PMCPMC7330577
OpenAlexW3039739816

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.