Evidence map›Paper›PMID 32622905›Full record

ArticleThe Journal of infection2020

Longitudinal anti-SARS-CoV-2 antibody profile and neutralization activity of a COVID-19 patient.

Shengxia Yin, Xin Tong, Aijun Huang, Han Shen, Yang Li, Yong Liu, Chao Wu, Rui Huang, Yuxin Chen

Abstract readCase ReportsLetter
In one paragraph

Article in The Journal of infection, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Isotyping and quantitation of the humoral immune response to SARS-CoV-2.Experimental biology and medicine (Maywood, N.J.) · 2022
    Article
  3. Equine immunoglobulin fragment F(ab')Clinical immunology (Orlando, Fla.) · 2022
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Shengxia YinDepartment of Infectious Diseases, Nanjing Drum Tower Hospital, Clinical College of Nanjing Medical University, Nanjing, Jiangsu, China.
Xin TongDepartment of Infectious Diseases, Nanjing Drum Tower Hospital, Clinical College of Nanjing Medical University, Nanjing, Jiangsu, China.
Aijun HuangDepartment of Laboratory Medicine, Nanjing Drum Tower Hospital, Nanjing University Medical School, Nanjing, Jiangsu, China.
Han ShenDepartment of Laboratory Medicine, Nanjing Drum Tower Hospital, Nanjing University Medical School, Nanjing, Jiangsu, China.
Yang LiDepartment of Laboratory Medicine, Nanjing Drum Tower Hospital, Nanjing University Medical School, Nanjing, Jiangsu, China.
Yong LiuDepartment of Experimental Medicine, Nanjing Drum Tower Hospital, Clinical College of Nanjing Medical University, Nanjing, Jiangsu, China.
Chao WuDepartment of Infectious Diseases, Nanjing Drum Tower Hospital, Clinical College of Nanjing Medical University, Nanjing, Jiangsu, China.
Rui HuangDepartment of Infectious Diseases, Nanjing Drum Tower Hospital, Clinical College of Nanjing Medical University, Nanjing, Jiangsu, China. Electronic address: doctor_hr@126.com.
Yuxin ChenDepartment of Laboratory Medicine, Nanjing Drum Tower Hospital, Nanjing University Medical School, Nanjing, Jiangsu, China. Electronic address: yuxin_chen2015@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We followed-up a mild COVID-19 patient for 91 days and serially monitored his serum antibodies to four SARS-CoV-2 related antigens (NP, RBD, S1 and ECD) and neutralization activities. Our data revealed a profile of serial antibody responses during the progress and a quick decline of neutralization activities after discharge.

Indexed as

AdultAntibodies, NeutralizingAntibodies, ViralAntigens, ViralBetacoronavirusCoronavirus InfectionsCOVID-19Enzyme-Linked Immunosorbent AssayHumansLongitudinal StudiesMaleNeutralization TestsPandemicsPneumonia, ViralRetrospective StudiesRNA, ViralAntibodies, NeutralizingAntibodies, ViralAntigens, ViralRNA, Viral

Identifiers

PMID32622905
PMCPMC7330586

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.