Evidence map›Paper›PMID 32622888›Full record

ArticleJournal of the American Academy of Dermatology2020

The spectrum of COVID-19-associated dermatologic manifestations: An international registry of 716 patients from 31 countries.

Esther E Freeman, Devon E McMahon, Jules B Lipoff, Misha Rosenbach, Carrie Kovarik, Seemal R Desai, Joanna Harp, Junko Takeshita, Lars E French, Henry W Lim and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of the American Academy of Dermatology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 175 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
175citing papers in PubMed, 4 pooled it
55.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

175 citing papers in PubMed, 4 syntheses or guidelines pooled it, 393 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. A comprehensive overview of monkeypox virus disease.Tropical medicine and health · 2026
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Review
  14. Review
  15. Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Review

115 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 9 institutions in 2 countries.

Esther E FreemanDepartment of Dermatology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts; Medical Practice Evaluation Center, Mongan Institute, Massachusetts General Hospital, Boston, Massachusetts. Electronic address: efreeman@mgh.harvard.edu.
Devon E McMahonDepartment of Dermatology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
Jules B LipoffDepartment of Dermatology, University of Pennsylvania, Philadelphia, Pennsylvania.
Misha RosenbachDepartment of Dermatology, University of Pennsylvania, Philadelphia, Pennsylvania.
Carrie KovarikDepartment of Dermatology, University of Pennsylvania, Philadelphia, Pennsylvania.
Seemal R DesaiDepartment of Dermatology, The University of Texas Southwestern Medical Center, Dallas, Texas; Innovative Dermatology, Plano, Texas.
Joanna HarpDepartment of Dermatology, Weill Cornell Medicine, New York, New York.
Junko TakeshitaDepartment of Dermatology, University of Pennsylvania, Philadelphia, Pennsylvania.
Lars E FrenchDepartment of Dermatology, University Hospital, Munich University of Ludwig Maximilian, Munich, Germany; Department of Dermatology, Dr Phillip Frost Department of Dermatology and Cutaneous Surgery, Miller School of Medicine, University of Miami, Miami, Florida.
Henry W LimDepartment of Dermatology, Henry Ford Health System, Detroit, Michigan.
Bruce H ThiersDepartment of Dermatology and Dermatologic Surgery, Medical University of South Carolina, Charleston, South Carolina.
George J HruzaDepartment of Dermatology, St. Louis University, St Louis, Missouri.
Lindy P FoxDepartment of Dermatology, University of California San Francisco, San Francisco, California.
University of Pennsylvania · USHarvard University · USHenry Ford Health System · USMedical University of South Carolina · USPlano Cancer Institute · USSaint Louis University · USUniversity of California, San Francisco · USUniversity of Miami · USWeill Cornell Medicine · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCoronavirus disease 2019 (COVID-19) has associated cutaneous manifestations.

objectiveTo characterize the diversity of cutaneous manifestations of COVID-19 and facilitate understanding of the underlying pathophysiology.

methodsCase series from an international registry from the American Academy of Dermatology and International League of Dermatological Societies.

resultsThe registry collected 716 cases of new-onset dermatologic symptoms in patients with confirmed/suspected COVID-19. Of the 171 patients in the registry with laboratory-confirmed COVID-19, the most common morphologies were morbilliform (22%), pernio-like (18%), urticarial (16%), macular erythema (13%), vesicular (11%), papulosquamous (9.9%), and retiform purpura (6.4%). Pernio-like lesions were common in patients with mild disease, whereas retiform purpura presented exclusively in ill, hospitalized patients. LIMITATIONS: We cannot estimate incidence or prevalence. Confirmation bias is possible.

conclusionsThis study highlights the array of cutaneous manifestations associated with COVID-19. Many morphologies were nonspecific, whereas others may provide insight into potential immune or inflammatory pathways in COVID-19 pathophysiology.

Indexed as

AdolescentAdultBetacoronavirusCoronavirus InfectionsCOVID-19FemaleHumansIncidenceMaleMiddle AgedPandemicsPneumonia, ViralRegistriesSARS-CoV-2Severity of Illness IndexSkin DiseasesCOVID-19COVID toesdermatologyglobal healthmacular erythemamorbilliformperniopublic healthregistryretiform purpuraSARS-CoV-2urticarialvesicular

Identifiers

PMID32622888
PMCPMC7331510
OpenAlexW3040595715

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.