Evidence map›Paper›PMID 32622016›Full record

ArticleResuscitation2020

Association between time of day and CPR quality as measured by CPR hemodynamics during pediatric in-hospital CPR.

Heather A Wolfe, Ryan W Morgan, Robert M Sutton, Ron W Reeder, Kathleen L Meert, Murray M Pollack, Andrew R Yates, John T Berger, Christopher J Newth, Joseph A Carcillo and 9 more

Open access · greenAbstract read
In one paragraph

Article in Resuscitation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Trial
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 16 institutions in 1 country.

Heather A WolfeDepartment of Anesthesiology and Critical Care Medicine, The Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, PA, United States. Electronic address: wolfeh@email.chop.edu.
Ryan W MorganDepartment of Anesthesiology and Critical Care Medicine, The Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, PA, United States.
Robert M SuttonDepartment of Anesthesiology and Critical Care Medicine, The Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, PA, United States.
Ron W ReederDepartment of Pediatrics, University of Utah, Salt Lake City, Utah, United States.
Kathleen L MeertDepartment of Pediatrics, Children's Hospital of Michigan, Wayne State University, Detroit, MI, United States.
Murray M PollackDepartment of Pediatrics, Children's National Medical Center, Washington D.C., United States; Department of Pediatrics, Phoenix Children's Hospital, Phoenix, AZ, United States.
Andrew R YatesDepartment of Pediatrics, Nationwide Children's Hospital, The Ohio State University, Columbus, OH, United States.
John T BergerDepartment of Pediatrics, Children's National Medical Center, Washington D.C., United States.
Christopher J NewthDepartment of Anesthesiology, Children's Hospital Los Angeles, University of Southern California Keck School of Medicine, Los Angeles, CA, United States.
Joseph A CarcilloDepartment of Critical Care Medicine, Children's Hospital of Pittsburgh, University of Pittsburgh, Pittsburgh, PA, United States.
Patrick S McQuillenDepartment of Pediatrics, Benioff Children's Hospital, University of California San Francisco, San Francisco, CA, United States.
Rick E HarrisonDepartment of Pediatrics, Mattel Children's Hospital, University of California Los Angeles, Los Angeles, CA, United States.
Frank W MolerDepartment of Pediatrics, C.S. Mott Children's Hospital, University of Michigan, MI, United States.
Todd C CarpenterDepartment of Pediatrics, Denver Children's Hospital, University of Colorado, Denver, CO, United States.
Daniel A NottermanDepartment of Molecular Biology, Princeton University, Princeton, New Jersey, United States.
J Michael DeanDepartment of Pediatrics, University of Utah, Salt Lake City, Utah, United States.
Vinay M NadkarniDepartment of Anesthesiology and Critical Care Medicine, The Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, PA, United States.
Robert A BergDepartment of Anesthesiology and Critical Care Medicine, The Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, PA, United States.
Eunice Kennedy Shriver National Institute of Child Health Human Development Collaborative Pediatric Critical Care Research Network Pediatric Intensive Care Quality of Cardiopulmonary Resuscitation (PICqCPR) investigators
Children's Hospital of Philadelphia · USPhiladelphia University · USUniversity of Utah · USChildren's Hospital of Los Angeles · USChildren's National · USC. S. Mott Children's Hospital · USNationwide Children's Hospital · USPhoenix Children's Hospital · USPrinceton University · USUniversity of California, Los Angeles · USUniversity of California, San Francisco · USUniversity of Colorado Denver · USUniversity of Pennsylvania · USUniversity of Pittsburgh · USUniversity of Southern California · USWayne State University · US

Funding

Data Coordinating Center for the Collaborative Pediatric Critical Care Research NetworkU01HD049934 · NICHD · UNIVERSITY OF UTAH · PI DEAN, JONATHAN MICHAEL · 2005 to 2020
$35.2M
Physiologically Guided Ventilator Strategies in ChildrenU10HD050012 · NICHD · CHILDREN'S HOSPITAL OF LOS ANGELES · PI NEWTH, CHRISTOPHER JOHN · 2005 to 2014
$3.7M
Collaborative Pediatric Critical Care Research Network (CPCCRN) at Children's NationalUG1HD049981 · NICHD · CHILDREN'S RESEARCH INSTITUTE · PI POLLACK, MURRAY MICHAEL, WESSEL, DAVID LLOYD · 2015 to 2020
$1.8M
Pediatric Critical Care Research Network at Children's Hospital of PhiladelphiaUG1HD063108 · NICHD · CHILDREN'S HOSP OF PHILADELPHIA · PI BERG, ROBERT ALLEN, ZUPPA, ATHENA F. · 2015 to 2020
$1.7M
Collaborative Research to Validate Biomarkers of Pediatric ARDSUG1HD083166 · NICHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MCQUILLEN, PATRICK SEAN, SAPRU, ANIL · 2015 to 2020
$1.6M
Renewal Application for the Childrens Hospital of Pittsburgh Collaborative Pediatric Critical Care Research Network SiteUG1HD049983 · NICHD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CARCILLO, JOSEPH A · 2015 to 2020
$1.6M
Collaborative Pediatric Critical Care Research NetworkUG1HD050096 · NICHD · WAYNE STATE UNIVERSITY · PI MEERT, KATHLEEN L. · 2015 to 2020
$1.6M
Collaborative Network Study of Airway Microbiome and Host Responses in Pediatric Respiratory FailureUG1HD083171 · NICHD · UNIVERSITY OF COLORADO DENVER · PI CARPENTER, TODD C · 2015 to 2020
$1.5M
Collaborative Pediatric Critical Care Research Network (UG1)UG1HD083170 · NICHD · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI HALL, MARK W · 2015 to 2020
$1.5M
Predicting Morbidity from Pediatric Critical CareU10HD063114 · NICHD · PHOENIX CHILDREN'S HOSPITAL · PI DALTON, HEIDI J, LUND, DENNIS P · 2010 to 2014
$1.4M
Collaborative Pediatric Research Critical Care Network(U10)U10HD063106 · NICHD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SHANLEY, THOMAS P. · 2010 to 2014
$1.3M
Collaborative Pediatric Critical Care Research Network - Clinical SiteRL1HD107773 · NICHD · CENTRAL MICHIGAN UNIVERSITY · PI KATHLEEN L. MEERT · 2021 to 2026
$862k
NHLBI NIH HHS K23 HL148541NICHD NIH HHS RL1 HD107773NICHD NIH HHS U01 HD049934NICHD NIH HHS U10 HD050012NICHD NIH HHS U10 HD063106NICHD NIH HHS U10 HD063114NICHD NIH HHS UG1 HD049981NICHD NIH HHS UG1 HD049983NICHD NIH HHS UG1 HD050096NICHD NIH HHS UG1 HD063108NICHD NIH HHS UG1 HD083166NICHD NIH HHS UG1 HD083170NICHD NIH HHS UG1 HD083171
6 · The paper itself

Abstract

introductionPatients who suffer in-hospital cardiac arrest (IHCA) are less likely to survive if the arrest occurs during nighttime versus daytime. Diastolic blood pressure (DBP) as a measure of chest compression quality was associated with survival from pediatric IHCA. We hypothesized that DBP during CPR for IHCA is lower during nighttime versus daytime.

methodsThis is a secondary analysis of data collected from the Pediatric Intensive Care Quality of Cardiopulmonary Resuscitation Study. Pediatric or Pediatric Cardiac Intensive Care Unit patients who received chest compressions for ≥1 min and who had invasive arterial BP monitoring were enrolled. Nighttime was defined as 11:00PM to 6:59AM and daytime as 7:00AM until 10:59PM. Primary outcome was attainment of DBP ≥ 25 mmHg in infants <1 year and ≥30 mmHg in older children. Secondary outcomes were mean DBP, ROSC, and survival to hospital discharge. Univariable and multivariate analyses evaluated the relationships between time (nighttime vs. daytime) and outcomes.

resultsBetween July 1, 2013 and June 30, 2016, 164 arrests met all inclusion/exclusion criteria: 45(27%) occurred at nighttime and 119(73%) during daytime. Average DBPs achieved were not different between groups (DBP: nighttime 28.3 mmHg[25.3, 36.5] vs. daytime 29.6 mmHg[21.8, 38.0], p = 0.64). Relative risk of DBP threshold met during nighttime vs. daytime was 1.27, 95%CI [0.80, 1.98], p = 0.30. There was no significant nighttime vs. daytime difference in ROSC (28/45[62%] vs. 84/119[71%] p = 0.35) or survival to hospital discharge (16/45[36%] vs. 61/119[51%], p = 0.08).

conclusionsIn this cohort of pediatric ICU patients with IHCA, there was no significant difference in DBP during CPR between nighttime and daytime.

Indexed as

Cardiopulmonary ResuscitationHeart ArrestBlood PressureChildHemodynamicsHospitals, PediatricHumansInfantCardiac arrestCardiopulmonary resuscitation (CPR)In-HospitalOutcomesPediatricSurvival

Identifiers

PMID32622016
PMCPMC7431912
OpenAlexW3038858725

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.