Evidence map›Paper›PMID 32621800›Full record

ArticleiScience2020

Morphological Evidence for an Oral Venom System in Caecilian Amphibians.

Pedro Luiz Mailho-Fontana, Marta Maria Antoniazzi, Cesar Alexandre, Daniel Carvalho Pimenta, Juliana Mozer Sciani, Edmund D Brodie, Carlos Jared

Open access · goldAbstract read
In one paragraph

Article in iScience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Pedro Luiz Mailho-FontanaStructural Biology Lab, Butantan Institute, São Paulo, Brazil.
Marta Maria AntoniazziStructural Biology Lab, Butantan Institute, São Paulo, Brazil.
Cesar AlexandreStructural Biology Lab, Butantan Institute, São Paulo, Brazil.
Daniel Carvalho PimentaBiochemistry Lab, Butantan Institute, São Paulo, Brazil.
Juliana Mozer ScianiSão Francisco University, Bragança Paulista, Brazil.
Edmund D BrodieBiology Department, Utah State University, Logan, USA.
Carlos JaredStructural Biology Lab, Butantan Institute, São Paulo, Brazil. Electronic address: carlos.jared@butantan.gov.br.
Instituto Butantan · BRUniversidade São Francisco · BRUtah State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Amphibians are known for their skin rich in glands containing toxins employed in passive chemical defense against predators, different from, for example, snakes that have active chemical defense, injecting their venom into the prey. Caecilians (Amphibia, Gymnophiona) are snake-shaped animals with fossorial habits, considered one of the least known vertebrate groups. We show here that amphibian caecilians, including species from the basal groups, besides having cutaneous poisonous glands as other amphibians do, possess specific glands at the base of the teeth that produce enzymes commonly found in venoms. Our analysis of the origin of these glands shows that they originate from the same tissue that gives rise to teeth, similar to the venom glands in reptiles. We speculate that caecilians might have independently developed mechanisms of production and injection of toxins early in their evolutionary history.

Indexed as

Biological SciencesEvolutionary BiologyZoology

Identifiers

PMID32621800
PMCPMC7385905
OpenAlexW3039069150

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.