Evidence map›Paper›PMID 32621246›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2021

Helicobacter pylori gastric infection in patients with laryngeal cancer and chronic laryngitis.

Ivana Pajić Matić, Ivo Matić, Siniša Maslovara, Karolina Veselski, Tomislav Stojadinović, Ivan Vučković

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In one paragraph

Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Effects of IntragastricJournal of clinical medicine · 2025
    Article
  2. Article
  3. Low Prevalence of HSV-1 andDiagnostics (Basel, Switzerland) · 2023
    Article
  4. Article
  5. LaryngealMicroorganisms · 2021
    Article
  6. Helicobacter pylori gastric infection in patients with laryngeal cancer.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Ivana Pajić MatićDepartment of ENT, Head and Neck Surgery, General Hospital "Dr. Josip Benčević", Andrije Štampara 42, 35000, Slavonski Brod, Croatia. ivanapp123@gmail.com.ORCID http://orcid.org/0000-0002-2997-711X
Ivo MatićDepartment of ENT, Head and Neck Surgery, General Hospital "Dr. Josip Benčević", Andrije Štampara 42, 35000, Slavonski Brod, Croatia.
Siniša MaslovaraDepartment of ENT, Head and Neck Surgery, General Hospital "Dr. Josip Benčević", Andrije Štampara 42, 35000, Slavonski Brod, Croatia.
Karolina VeselskiDepartment of ENT, Head and Neck Surgery, General Hospital "Dr. Josip Benčević", Andrije Štampara 42, 35000, Slavonski Brod, Croatia.
Tomislav StojadinovićDepartment of ENT, Head and Neck Surgery, General Hospital "Dr. Josip Benčević", Andrije Štampara 42, 35000, Slavonski Brod, Croatia.
Ivan VučkovićDepartment of ENT, Head and Neck Surgery, General Hospital "Dr. Josip Benčević", Andrije Štampara 42, 35000, Slavonski Brod, Croatia.
University of Slavonski Brod · HRPolytechnic Lavoslav Ružička Vukovar · HR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe purpose of this study was to investigate the pathohistological status of mucous lining infected with Helicobacte pylori as the possible cause of chronic laryngitis and laryngeal carcinoma. MATERIALS AND

methodsThe prospective examination included 51 patients suffering from planocellular laryngeal cancer and 26 examinees suffering from chronic laryngitis. The examinees and the control group were subjected to esophagogastroduodenoscopy which described the local status of the esophagus and stomach. Two biopsy samplings are taken from the stomach antrum and corpus. One part of the biopsies was colored using the histological technique used in the pathohistological detection of H. pylori, while the other part was incorporated in paraffin cubes where the H. Pylori gene expression was determined using the deparaffinization and PCR method DNA isolation.

resultsIn the group of examinees suffering from laryngeal tumor, there were a higher number of patients suffering also from chronic gastritis (32/51) than in the other group, suffering from chronic laryngitis (9/26). In the chronic laryngitis group, there were more examinees with acute gastritis (12/26) than in the examined group (11/51). The difference is statistically significant (p = 0.0457).

conclusionChronic gastritis and H. pylori infection are risk factors for laryngeal carcinoma formation; therefore, acute gastritis with helicobacter pylori infection must be immediately treated to not let infection to become chronic.

Indexed as

AgedBiopsyCase-Control StudiesEndoscopy, Digestive SystemFemaleGastritisHelicobacter InfectionsHelicobacter pyloriHumansLaryngeal NeoplasmsLaryngitisLarynxMaleMiddle AgedPolymerase Chain ReactionProspective StudiesChronic laryngitisGastritisH. pyloriLaryngeal carcinoma

Identifiers

PMID32621246
OpenAlexW3039510520

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.