Evidence map›Paper›PMID 32621212›Full record

ArticleJournal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing2021

Is the time of atrial fibrillation recurrence after cryoballoon ablation of paroxysmal atrial fibrillation influenced by the pattern of PV reconnections?

Marcus Wieczorek, Kiarash Sassani, Reinhard Hoeltgen

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Article in Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Marcus WieczorekSchool of Medicine, Witten/Herdecke University, Witten, Germany. drmwieczorek@t-online.de.ORCID http://orcid.org/0000-0002-9621-7559
Kiarash SassaniDepartment of Cardiology and Electrophysiology, St. Agnes-Hospital, Barloer Weg 125, 46397, Bocholt, Germany.
Reinhard HoeltgenDepartment of Cardiology and Electrophysiology, St. Agnes-Hospital, Barloer Weg 125, 46397, Bocholt, Germany.
BMW (Germany) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPulmonary vein isolation (PVI) with 2nd-generation cryoballoon (CB) has been shown to be effective in the treatment of paroxysmal atrial fibrillation (AF). We describe pulmonary vein (PV) reconnection at repeat ablation in patients with AF recurrence after CB PVI and analyze the correlation between the time of AF recurrence and the observed PV reconnection patterns.

methodsSixty-six patients undergoing a redo PVI for recurrent AF were enrolled 9.1 ± 2.6 months after the initial CB PVI procedure.

resultsNinety-two percent had PV reconnections with a mean of 1.97 ± 0.8 reconnected PVs/patient, and 52% of formerly isolated PVs were found reconnected. The highest reconnected rates were observed for left superior PVs (67%). Fifty-three percent of the patients had 2 reconnected PVs, no patient had all PVs reconnected, and 8% were without PV reconnection. There was a significant negative correlation between the time of AF recurrences and the extent of PV reconnections at redo PVI for patients with proven PV reconnection in more than one PV (R = 0.52, p < 0.001), while all patients without PV reconnection had AF recurrences within the first 9 months after PVI.

conclusionsAt redo ablation, most patients with recurrence of AF after CB PVI had PV reconnection(s). Patients with PV reconnection(s) showed a negative correlation between the number of reconnected PVs and the time of AF recurrence with more extensive PV reconnections resulting in earlier PV recurrences after the blanking period. Patients without PV reconnection experienced early AF recurrences, indicating non-PV triggers contributing for paroxysmal AF recurrences in these patients.

Indexed as

Atrial FibrillationCatheter AblationCryosurgeryPulmonary VeinsHumansRecurrenceTreatment OutcomeCryoballoonParoxysmal atrial fibrillation recurrencePhased radiofrequencyPulmonary vein isolationPulmonary vein reconnection

Identifiers

PMID32621212
OpenAlexW3038965176

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.