ArticleLasers in medical science2021
Effects of green light photobiomodulation on Dental Pulp Stem Cells: enhanced proliferation and improved wound healing by cytoskeleton reorganization and cell softening.
Article in Lasers in medical science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.
- A Comprehensive Systematic Review of the Effects of Photobiomodulation Therapy in Different Light Wavelength Ranges (Blue, Green, Red, and Near-Infrared) on Sperm Cell Characteristics in Vitro and in Vivo.Reproductive sciences (Thousand Oaks, Calif.) · 2024Pooled it
- Photobiomodulation-induced Differentiation of Adipose-derived Stem Cells into Neuronal Organoid-like Structures.Molecular neurobiology · 2026Article
- Cellular homeostasis and oncology safety of low pulse frequency laser for photobiomodulation in oral and dermal cells.Lasers in medical science · 2026Article
- Photobiomodulation-Driven Tenogenic Differentiation of MSCs in Hydrogel Culture.International journal of molecular sciences · 2025Article
- Advances in Photobiomodulation: Effects on Mesenchymal Stem Cells and their Paracrine Factors.Stem cell reviews and reports · 2025Review
- The effect of blue and green light on human umbilical cord mesenchymal stem cells for promoting proliferation and wound healing.Scientific reports · 2025Article
- Photobiomodulation in fibroblasts: from light to healing through molecular pathways, omics and artificial intelligence.Frontiers in bioengineering and biotechnology · 2025Review
- Effect of Photobiomodulation Therapy with Three Wavelengths of Diode Laser on Proliferation and Survival of Stem Cells Derived from Impacted Third Molar Follicles.Journal of lasers in medical sciences · 2025Article
- Regenerative endodontic therapy in immature teeth using photobiomodulation and photodynamic therapy; a histomorphological study in canine model.BMC oral health · 2024Article
- Effects of Semiconductor Laser Irradiation on Differentiation of Human Dental Pulp Stem Cells in Co-Culture with Dentin.Dentistry journal · 2024Article
- Photobiomodulation at molecular, cellular, and systemic levels.Lasers in medical science · 2023Review
- Photobiomodulation Therapy Affects the Elastic Modulus, Cytoskeletal Rearrangement and Migration Capability of Human Osteosarcoma Cells.Lasers in medical science · 2022Article
- Dental-Derived Mesenchymal Stem Cells: State of the Art.Frontiers in cell and developmental biology · 2021Review
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Photobiomodulation (PBM) has been shown to improve cell proliferation and cell migration. Many cell types have been investigated, with most studies using deep penetrating red light irradiation. Considering the interest of surface biostimulation of oral mesenchymal cells after surgical wound, the present study aimed to assess green light irradiation effects on Dental Pulp Stem Cells' (DPSC) proliferation and migration. To understand the mechanisms underlying these effects, we investigated cytoskeleton organization and subsequent cell shape and stiffness. A 532-nm wavelength Nd:YAG laser (30 mW) was applied between 30 and 600 s on DPSC in vitro. Cell proliferation was analyzed at 24, 48, and 72 h after irradiation, by cell counting and enzymatic activity quantification (paranitrophenylphosphate phosphatase (pNPP) test). A wound healing assay was used to study cell migration after irradiation. Effects of PBM on cytoskeleton organization and cell shape were assessed by actin filaments staining. Elasticity changes after irradiation were quantified in terms of Young's modulus measured using Atomic Force Microscopy (AFM) force spectroscopy. Green light significantly improved DPSC proliferation with a maximal effect obtained after 300-s irradiation (energy fluence 5 J/cm
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.