Evidence map›Paper›PMID 32621061›Full record

ArticleSkeletal radiology2021

Marrow uptake on FDG PET/CT is associated with progression from smoldering to symptomatic multiple myeloma.

Behrang Amini, Yves-Paul N Nakache, Lorenzo Nardo, Elisabet E Manasanch, Jia Sun, Leon Lenchik, Robert D Boutin

Abstract read
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In one paragraph

Article in Skeletal radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Behrang AminiDepartment of Musculoskeletal Imaging, The University of Texas, MD Anderson Cancer Center, 1515 Holcombe Blvd, Unit 1475, Houston, TX, 77030, USA. bamini@mdanderson.org.ORCID http://orcid.org/0000-0002-4962-3466
Yves-Paul N NakacheDepartment of Radiology, The University of California, Davis, Davis, CA, USA.
Lorenzo NardoDepartment of Radiology, The University of California, Davis, Davis, CA, USA.
Elisabet E ManasanchDepartment of Lymphoma/Myeloma, The University of Texas, M.D. Anderson Cancer Center, Houston, TX, USA.
Jia SunDepartment of Biostatistics, The University of Texas, M.D. Anderson Cancer Center, Houston, TX, USA.
Leon LenchikDepartment of Diagnostic Radiology, Wake Forest School of Medicine, Winston-Salem, NC, USA.
Robert D BoutinDepartment of Diagnostic Radiology, Stanford University, Stanford, CA, USA.
The University of Texas MD Anderson Cancer Center · USUniversity of California, Davis · USStanford University · USWake Forest University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine association of body composition measurements on CT and PET with progression of smoldering myeloma to multiple myeloma.

methodsA retrospective cohort study in 65 patients with smoldering myeloma and PET/CT at diagnosis was performed at a tertiary cancer center. Subjects were between 38 and 87 years of age (mean 64) and included 37 males. Primary outcome was progression-free survival as a function of bone, fat, and muscle metrics on CT and PET (measured at the level of L4 pedicles) and clinical confounders. CT metrics included attenuation of L4 and retroperitoneal fat and various indices derived from the psoas muscle. PET measures included SUV

resultsSUV

conclusionSUV of L4 is a prognostic indicator in patients with smoldering myeloma.

Indexed as

Fluorodeoxyglucose F18Multiple MyelomaBone MarrowHumansMaleMultimodal ImagingPositron-Emission TomographyPositron Emission Tomography Computed TomographyRadiopharmaceuticalsRetrospective StudiesFluorodeoxyglucose F18RadiopharmaceuticalsFDG PET/CTMultiple myelomaSmoldering myeloma

Identifiers

PMID32621061
OpenAlexW3039905770

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.