SynthesisNeuroradiology2020
Dual-energy CT for differentiating acute intracranial hemorrhage from contrast staining or calcification: a meta-analysis.
Synthesis in Neuroradiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Diagnostic performance of dual-energy CT for differentiating acute intracranial hemorrhage from contrast staining: a systematic review and meta-analysis.Frontiers in medicine · 2025Pooled it
- Diagnostic accuracy of dual-energy computed tomography in the diagnosis of neurological complications after endovascular treatment of acute ischaemic stroke: a systematic review and meta-analysis.The British journal of radiology · 2024Pooled it
- Diagnostic accuracy of dual-energy computed tomography to differentiate intracerebral hemorrhage from contrast extravasation after endovascular thrombectomy for acute ischemic stroke: systematic review and meta-analysis.European radiology · 2022Pooled it
- What you don't see matters: dual-energy CT in emergency radiology.Japanese journal of radiology · 2026Review
- Radiomics model based on dual-energy CTA reconstructed images of infarcted brain tissue to predict malignant cerebral edema in stroke patients.Neuroradiology · 2026Article
- Dual-energy computed tomography in children: Technique and clinical applications.World journal of clinical pediatrics · 2025Review
- Applications of spectral CT in emergency department imaging, with a focus on neuroimaging.Emergency radiology · 2025Review
- Clinical Applications of Dual-Energy Computed Tomography for Acute Ischemic Stroke.Stroke (Hoboken, N.J.) · 2024Review
- Discrimination of Hemorrhage and Contrast Media in a Head Phantom on Photon-Counting Detector CT Data.AJNR. American journal of neuroradiology · 2024Article
- Determinants and Clinical Relevance of Iodine Contrast Extravasation after Endovascular Thrombectomy: A Dual-Energy CT Study.AJNR. American journal of neuroradiology · 2023Article
- Early antithrombotic therapy in patients with postinterventional cerebral hyperdensity reduces early neurological deterioration after mechanical thrombectomy.BMC neurology · 2023Article
- Dual-Energy Computed Tomography in Stroke Imaging : Value of a New Image Acquisition Technique for Ischemia Detection after Mechanical Thrombectomy.Clinical neuroradiology · 2023Article
- A Novel Dual-Energy CT Method for Detection and Differentiation of Intracerebral Hemorrhage From Contrast Extravasation in Stroke Patients After Endovascular Thrombectomy : Feasibility and First Results.Clinical neuroradiology · 2023Article
- DECT Numbers in Upper Abdominal Organs for Differential Diagnosis: A Feasibility Study.Tomography (Ann Arbor, Mich.) · 2022Article
- Dual-Energy CT for Accurate Discrimination of Intraperitoneal Hematoma and Intestinal Structures.Diagnostics (Basel, Switzerland) · 2022Article
- Initial experience with dual-layer detector spectral CT for diagnosis of blood or contrast after endovascular treatment for ischemic stroke.Neuroradiology · 2022Article
- Review
- Intracranial Bleeding After Reperfusion Therapy in Acute Ischemic Stroke.Frontiers in neurology · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study aimed to comprehensively evaluate the diagnostic performance of dual-energy CT (DECT) for differentiating acute intracranial hemorrhage (ICH) from contrast staining or small calcifications via a systematic review and meta-analysis.
methodsThe PubMed-MEDLINE, EMBASE, and Cochrane Library databases were searched up to November 10, 2019. Original studies (prospective or retrospective cohort studies) with the primary aim of detecting ICH using DECT were selected. The diagnostic performance of DECT was assessed using bivariate and hierarchical summary receiver operating characteristic models. Quality assessment was performed according to the Quality Assessment of Diagnostic Accuracy Studies-2, while between-study heterogeneity was assessed using Higgins' inconsistency index (I
resultsNine studies comprising 402 patients with 453 lesions were included for data synthesis. The overall pooled sensitivity and specificity of DECT for ICH detection were 96% (95% CI, 77-99%) and 98% (95 CI, 93%-100%), respectively. Substantial and moderate between-study heterogeneities were observed for sensitivity (I
conclusionDECT demonstrated excellent diagnostic performance in terms of differentiating acute ICH from contrast staining and small calcifications. However, publication bias suggests the possibility of overestimated diagnostic performance, warranting large-scale, prospective cohort studies.
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Registered trials
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