Evidence map›Paper›PMID 32620896›Full record

ArticleHypertension research : official journal of the Japanese Society of Hypertension2020

Impact of hypertension stratified by diabetes on the lifetime risk of cardiovascular disease mortality in Japan: a pooled analysis of data from the Evidence for Cardiovascular Prevention from Observational Cohorts in Japan study.

Yukiko Imai, Takumi Hirata, Shigeyuki Saitoh, Toshiharu Ninomiya, Yoshihiro Miyamoto, Hirofumi Ohnishi, Yoshitaka Murakami, Hiroyasu Iso, Sachiko Tanaka, Katsuyuki Miura and 7 more

Abstract read
PubMed Publisher
In one paragraph

Article in Hypertension research : official journal of the Japanese Society of Hypertension, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Current hypertension epidemiology and contemporary approaches using the "Real-World Evidence Cycle" framework.Hypertension research : official journal of the Japanese Society of Hypertension · 2026
    Review
  2. Article
  3. Article
  4. Long-term risk of cardiovascular mortality according to age group and blood pressure categories of the latest guideline.Hypertension research : official journal of the Japanese Society of Hypertension · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Annual reports on hypertension research 2020.Hypertension research : official journal of the Japanese Society of Hypertension · 2022
    Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Yukiko ImaiDepartment of Preventive Medicine and Public Health, School of Medicine, Keio University, Tokyo, Japan.
Takumi HirataDepartment of Public Health, Faculty of Medicine, Hokkaido University, Sapporo, Japan. t-hirata@med.hokudai.ac.jp.
Shigeyuki SaitohDepartment of Nursing, School of Health Sciences, Sapporo Medical University, Sapporo, Japan.
Toshiharu NinomiyaDepartment of Epidemiology and Public Health, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Yoshihiro MiyamotoDepartment of Preventive Medicine and Epidemiologic Informatics, National Cerebral and Cardiovascular Center, Suita, Japan.
Hirofumi OhnishiDepartment of Public Health, Sapporo Medical University, Sapporo, Japan.
Yoshitaka MurakamiDepartment of Medical Statistics, School of Medicine, Toho University, Tokyo, Japan.
Hiroyasu IsoDepartment of Social and Environmental Medicine, Graduate School of Medicine, Osaka University, Suita, Japan.
Sachiko TanakaDepartment of Public Health, Center for Epidemiologic Research in Asia, Shiga University of Medical Science, Shiga, Japan.
Katsuyuki MiuraDepartment of Public Health, Center for Epidemiologic Research in Asia, Shiga University of Medical Science, Shiga, Japan.
Akiko TamakoshiDepartment of Public Health, Faculty of Medicine, Hokkaido University, Sapporo, Japan.
Michiko YamadaDepartment of Clinical Studies, Radiation Effects Research Foundation, Hiroshima, Japan.
Masahiko KiyamaOsaka Center for Cancer and Cardiovascular Disease Prevention, Osaka, Japan.
Hirotsugu UeshimaDepartment of Public Health, Center for Epidemiologic Research in Asia, Shiga University of Medical Science, Shiga, Japan.
Shizukiyo IshikawaMedical Education Center, Jichi Medical University, Tochigi, Japan.
Tomonori OkamuraDepartment of Preventive Medicine and Public Health, School of Medicine, Keio University, Tokyo, Japan.
Evidence for Cardiovascular Prevention from Observational Cohorts in Japan (EPOCH-JAPAN) Research Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lifetime risk is an informative estimate to motivate people to change lifestyle behaviors, especially from a younger age, in public health education. The impact of the combination of hypertension and diabetes on the lifetime risk of cardiovascular mortality has not been investigated in Asian populations. A pooled analysis of individual data from nine cohorts was performed. A total of 57,339 Japanese men and women were eligible for the analysis. We used the modified Kaplan-Meier approach and estimated the remaining lifetime risk of cardiovascular mortality starting from the index age of 35 years. Participants were classified into four categories defined by hypertension and diabetes. The lifetime risk was increased in the order of those without either risk, those without hypertension but with diabetes, those with hypertension but without diabetes, and those with both risks. The lifetime risk of cardiovascular mortality at the 35-year index age was as follows: 7.8% in men and 6.2% in women for those without either hypertension or diabetes, 13.2% in men and 9.5% in women for those without hypertension but with diabetes, 17.2% in men and 11.7% in women for those with hypertension but without diabetes, and 19.4% in men and 15% in women for those with both risks. These findings reinforce the need for a life-course perspective in the management of hypertension and diabetes from a younger age.

Indexed as

Cohort StudiesDiabetes ComplicationsHumansHypertensionJapanRisk AssessmentCardiovascular diseasesDiabetesEpidemiologyHypertensionLifetime risk

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.