Evidence map›Paper›PMID 32620847›Full record

ArticleScientific reports2020

Increased Alcohol Consumption in Mice Lacking Sodium Bicarbonate Transporter NBCn1.

Jesse R Schank, Soojung Lee, Carlos E Gonzalez-Islas, Sadie E Nennig, Hannah D Fulenwider, Jianjun Chang, Jun Ming Li, Yejin Kim, Lauren A Jeffers, Jaegwon Chung and 5 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Loss of NaActa physiologica (Oxford, England) · 2025
    Article
  3. Sodium Bicarbonate Decreases Alcohol Consumption in Mice.International journal of molecular sciences · 2024
    Article
  4. Antibodies toward NaBritish journal of cancer · 2024
    Article
  5. Potential Theranostic Roles of SLC4 Molecules in Human Diseases.International journal of molecular sciences · 2023
    Review
  6. Understanding the Physiological Role of Electroneutral NaPharmaceuticals (Basel, Switzerland) · 2022
    Review
  7. Bicarbonate-Independent Sodium Conductance of Na/HCOCurrent issues in molecular biology · 2022
    Article
  8. Decreased Brain pH and Pathophysiology in Schizophrenia.International journal of molecular sciences · 2021
    Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 3 countries.

Jesse R SchankDepartment of Physiology and Pharmacology, University of Georgia College of Veterinary Medicine, Athens, GA, 30602, USA.
Soojung LeeDepartment of Physiology, Emory University School of Medicine, Atlanta, GA, 30322, USA.
Carlos E Gonzalez-IslasDepartment of Physiology, Emory University School of Medicine, Atlanta, GA, 30322, USA.
Sadie E NennigDepartment of Physiology and Pharmacology, University of Georgia College of Veterinary Medicine, Athens, GA, 30602, USA.
Hannah D FulenwiderDepartment of Physiology and Pharmacology, University of Georgia College of Veterinary Medicine, Athens, GA, 30602, USA.
Jianjun ChangDepartment of Physiology, Emory University School of Medicine, Atlanta, GA, 30322, USA.
Jun Ming LiDepartment of Physiology, Emory University School of Medicine, Atlanta, GA, 30322, USA.
Yejin KimDepartment of Physiology, Emory University School of Medicine, Atlanta, GA, 30322, USA.
Lauren A JeffersDepartment of Medicine, Pulmonary Division, Emory University School of Medicine, Atlanta, GA, 30322, USA.
Jaegwon ChungDepartment of Physiology and Pharmacology, University of Georgia College of Veterinary Medicine, Athens, GA, 30602, USA.
Jae-Kyung LeeDepartment of Physiology and Pharmacology, University of Georgia College of Veterinary Medicine, Athens, GA, 30602, USA.
Zhe JinDepartment of Neuroscience, Uppsala University, Uppsala, 75124, Sweden.
Christian AalkjaerDepartment of Biomedicine, Aarhus University, 8000, Aarhus C, Denmark.
Ebbe BoedtkjerDepartment of Biomedicine, Aarhus University, 8000, Aarhus C, Denmark.
Inyeong ChoiDepartment of Physiology, Emory University School of Medicine, Atlanta, GA, 30322, USA. ichoi@emory.edu.
Emory University · USGeorgia College & State University · USAarhus University · DKUppsala University · SE

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM008169 · NIGMS · EMORY UNIVERSITY · PI GROSS, ROBERT E · 1987 to 2021
$20.3M
Brain Tissue Resource Centre for Alcohol ResearchR28AA012725 · NIAAA · UNIVERSITY OF SYDNEY · PI Greg Trevor Sutherland · 2012 to 2026
$7.0M
Structure/function analysis of the na/bicarbonate cotransportersR01GM078502 · NIGMS · EMORY UNIVERSITY · PI CHOI, INYEONG · 2007 to 2011
$1.6M
The Role of the Neurokinin-1 Receptor and NF kappa B in alcohol-induced behaviorR00AA021805 · NIAAA · UNIVERSITY OF GEORGIA · PI SCHANK, JESSE R · 2014 to 2016
$724k
NIAAA NIH HHS R00 AA021805NIAAA NIH HHS R28 AA012725NIGMS NIH HHS R01 GM078502NIGMS NIH HHS T32 GM008169
6 · The paper itself

Abstract

The previous reports on an addiction vulnerability marker in the human SLC4A7 gene encoding the Na/HCO

Indexed as

Down-RegulationAlcohol DrinkingAnimalsCells, CulturedGene Knockout TechniquesHippocampusHumansHydrogen-Ion ConcentrationMaleMiceNeuronsQuinineSodium-Bicarbonate SymportersSucroseQuinineSLC4A7 protein, humanSlc4a7 protein, mouseSodium-Bicarbonate SymportersSucrose

Identifiers

PMID32620847
PMCPMC7335059
OpenAlexW3034178618

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.