ArticleNature communications2020
Anatomically and functionally distinct thalamocortical inputs to primary and secondary mouse whisker somatosensory cortices.
Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers.
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Who cites it
72 citing papers in PubMed, 144 citations in OpenAlex.
- δ2-Protocadherins organize parallel indirect basal ganglia circuits.Science advances · 2026Article
- Neuronal ensembles in cortical function and disease.Physiological reviews · 2026Review
- Retrosplenial cortex enables context-dependent goal-directed sensorimotor transformation.eLife · 2026Article
- Mild Focal Cooling Decouples Dendrites to Reconfigure Cortical Output.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- The role of transthalamic pathways in perception.Communications biology · 2026Review
- Modulation and Gating of Transthalamic and Subcortical Pathways through Somatosensory Thalamus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Presynaptic control of top-down signaling in neocortical layer 1.bioRxiv : the preprint server for biology · 2026Article
- A Corticotectal Pathway Regulates Vibrissal Somatosensory-Mediated Predatory Hunting Learning.Research (Washington, D.C.) · 2026Article
- Synergistic effects of cerebral small vessel disease burden and plasma phosphorylated tau 181 on white matter microstructure and cognition in a Chinese cohort.Brain communications · 2026Article
- An adaptive and flexible role for primary sensory cortex.Nature neuroscience · 2026Review
- Impact of endogenous sonosensation oniScience · 2025Article
- Pathway-Specific Ultrastructure of Thalamocortical Synapses in Mouse Somatosensory Area S2.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Chronic fluoxetine modulates perineuronal nets and inhibitory neuronal function in relation to behavioral outcomes.IBRO neuroscience reports · 2025Article
- Article
- Noncanonical short-latency auditory pathway directly activates deep cortical layers.Nature communications · 2025Article
- Role of posterior medial thalamus in the modulation of striatal circuitry and choice behavior.eLife · 2025Article
- Active and passive touch are differentially represented in the mouse somatosensory thalamus.PLoS biology · 2025Article
- Cholecystokinin neurons in the spinal trigeminal nucleus interpolaris regulate mechanically evoked predatory hunting in male mice.Nature communications · 2025Article
- Stimulus selection enhances value-modulated somatosensory processing in the superior colliculus.PLoS biology · 2025Article
- Distinct Roles of Astrocytes and GABAergic Neurons in the Paraventricular Thalamic Nucleus in Modulating Diabetic Neuropathic Pain.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
12 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Subdivisions of mouse whisker somatosensory thalamus project to cortex in a region-specific and layer-specific manner. However, a clear anatomical dissection of these pathways and their functional properties during whisker sensation is lacking. Here, we use anterograde trans-synaptic viral vectors to identify three specific thalamic subpopulations based on their connectivity with brainstem. The principal trigeminal nucleus innervates ventral posterior medial thalamus, which conveys whisker-selective tactile information to layer 4 primary somatosensory cortex that is highly sensitive to self-initiated movements. The spinal trigeminal nucleus innervates a rostral part of the posterior medial (POm) thalamus, signaling whisker-selective sensory information, as well as decision-related information during a goal-directed behavior, to layer 4 secondary somatosensory cortex. A caudal part of the POm, which apparently does not receive brainstem input, innervates layer 1 and 5A, responding with little whisker selectivity, but showing decision-related modulation. Our results suggest the existence of complementary segregated information streams to somatosensory cortices.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.