Observational studyPediatrics2020
Weight as a Risk Factor for Mortality in Critically Ill Patients.
Observational study in Pediatrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.
- Impact of underweight status on mortality in sepsis patients: a meta-analysis.Frontiers in medicine · 2025Pooled it
- Feeding or Failing? Rethinking Nutrition Therapy in Pediatric Critical Care.Current nutrition reports · 2026Review
- Nationwide trends in pediatric obesity in Thailand, 2015-2023: prevalence, morbidity, mortality, and COVID-19-related disparities.BMC public health · 2026Article
- Weight changes and all-cause mortality in critically ill patients: a multi-center retrospective cohort study.Frontiers in nutrition · 2026Article
- Height status matters for risk of mortality in critically ill children.Journal of intensive care · 2024Article
- Multi-center retrospective study of children with sickle cell disease admitted to pediatric intensive care units in the United States.Scientific reports · 2023Article
- Preclinical Mouse Models in Sepsis: Don't Throw the Baby Out with the Bathwater [Response to Letter].Journal of inflammation research · 2023Article
- The Role of Childhood Obesity in Acute Presentations and Outcomes of Hospitalized COVID-19 Patients.Cureus · 2022Article
- The Impact of Obesity on Critical Illnesses.Shock (Augusta, Ga.) · 2021Review
- Low Body Mass Index as a Predictive Factor for Postoperative Infectious Complications after Ureterorenoscopic Lithotripsy.Medicina (Kaunas, Lithuania) · 2021Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
Abstract
objectivesTo explore the hypothesis that obesity is associated with increased mortality and worse outcomes in children who are critically ill.
methodsSecondary analysis of the Assessment of Worldwide Acute Kidney Injury, Renal Angina, and Epidemiology study, a prospective, multinational observational study. Patients between 3 months and 25 years across Asia, Australia, Europe, and North America were recruited for 3 consecutive months. Patients were divided into 4 groups (underweight, normal weight, overweight, and obese) on the basis of their BMI percentile for age and sex.
resultsA total of 3719 patients were evaluated, of whom 542 (14%) had a primary diagnosis of sepsis. One thousand fifty-nine patients (29%) were underweight, 1649 (44%) were normal weight, 423 (11%) were overweight, and 588 (16%) were obese. The 28-day mortality rate was 3.6% for the overall cohort and 9.1% for the sepsis subcohort and differed significantly by weight status (5.8%, 3.1%, 2.2%, and 1.8% for subjects with underweight, normal weight, overweight, and obesity, respectively, in the overall cohort [
conclusionsPatients who are underweight make up a significant proportion of all patients in the PICU, have a higher short-term mortality rate, and have a more complicated ICU course.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.