ReviewExpert review of clinical immunology2020
Swinging the pendulum: lessons learned from public discourse concerning hydroxychloroquine and COVID-19.
Review in Expert review of clinical immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Use of hydroxychloroquine and chloroquine in patients with COVID-19: a meta-analysis of randomized clinical trials.Pathogens and global health · 2021Pooled it
- An Electronic Dashboard to Improve Dosing of Hydroxychloroquine Within the Veterans Health Care System: Time Series Analysis.JMIR medical informatics · 2023Article
- A mixed methods study exploring requests for unproven COVID therapies such as ivermectin and healthcare distrust in the rural South.Preventive medicine reports · 2023Article
- Social Media for Research Discourse, Dissemination, and Collaboration in Rheumatology.Rheumatology and immunology research · 2022Article
- Analysis of the Prophylactic use of Hydroxychloroquine at the Beginning of the COVID-19 Pandemic Among Physicians.Infectious diseases & clinical microbiology · 2022Article
- The Promises and Perils of Social Media for Pediatric Rheumatology.Rheumatic diseases clinics of North America · 2022Review
- Prevalence of coronavirus disease 2019 in a multiethnic cohort of patients with autoimmune rheumatic diseases in Qatar.Qatar medical journal · 2022Article
- Article
- Formulating Hypotheses for Different Study Designs.Journal of Korean medical science · 2021Review
- Science's Response to CoVID-19.ChemMedChem · 2021Review
- What cannabis can learn from Covid: Hydroxychloroquine research suggests the next step for medical cannabis research.The International journal on drug policy · 2021Article
- Open science saves lives: lessons from the COVID-19 pandemic.BMC medical research methodology · 2021Article
- COVID-19 and the generation of novel scientific knowledge: Research questions and study designs.Journal of evaluation in clinical practice · 2021Article
- COVID-19 and Disease-Modifying Anti-rheumatic Drugs.Current rheumatology reports · 2021Review
- French Public Familiarity and Attitudes toward Clinical Research during the COVID-19 Pandemic.International journal of environmental research and public health · 2021Article
- Global research collaboration in a pandemic-challenges and opportunities: the COVID-19 Global Rheumatology Alliance.Current opinion in rheumatology · 2021Review
- Hydroxychloroquine for the treatment of COVID-19 and its potential cardiovascular toxicity: Hero or villain?Best practice & research. Clinical rheumatology · 2021Review
- Challenges of Egyptian patients with systemic lupus erythematosus during the COVID-19 pandemic.Reumatologia · 2021Article
- Clinical pathways for patients with giant cell arteritis during the COVID-19 pandemic: an international perspective.The Lancet. Rheumatology · 2021Review
- Trends in COVID-19 cases and clinical management in Veterans Health Administration medical facilities: A national cohort study.PloS one · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors.
Funding
Abstract
introductionSeveral months into the COVID-19 pandemic, safe and effective treatments against this global health disaster have yet to be identified. Clinical research trials around the world are underway testing a wide array of possible medications. In particular, the off-label use of hydroxychloroquine for COVID-19 prophylaxis and treatment has created many unprecedented challenges for the scientific community and the public. AREAS COVERED: We critically assessed major events from February - May 2020 that contributed to widespread use of hydroxychloroquine for the treatment and prophylaxis of COVID-19. We aimed to explore how opinions toward hydroxychloroquine may shift from early enthusiasm (based on EXPERT OPINION: Mindful and rigorous acquisition of data, as well as its interpretation, are essential to an effective pandemic response. The rapid and premature promotion of results has had major implications for global crisis management, even creating distrust among the public. It is crucial for the medical and scientific community to incorporate the lessons learned from this situation.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.