Evidence map›Paper›PMID 32619815›Full record

Observational studyAmerican heart journal2020

Acute myocardial infarction under-diagnosis and mortality in a Tanzanian emergency department: A prospective observational study.

Julian T Hertz, Francis M Sakita, Godfrey L Kweka, Alexander T Limkakeng, Sophie W Galson, Jinny J Ye, Tumsifu G Tarimo, Gloria Temu, Nathan M Thielman, Janet P Bettger and 3 more

Abstract readObservational Study
In one paragraph

Observational study in American heart journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Observational
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Acute coronary syndrome prevalence and outcomes in a Tanzanian emergency department: Results from a prospective surveillance study.African journal of emergency medicine : Revue africaine de la medecine d'urgence · 2025
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Evaluating the performance of the HEART score in a Tanzanian emergency department.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2024
    Observational
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Julian T HertzDivision of Emergency Medicine, Duke University School of Medicine, 2301 Erwin Rd, Durham, NC; Duke Global Health Institute, 310 Trent Drive, Durham, NC; Reprint requests: Julian T. Hertz, MD, MScGH, Division of Emergency Medicine, Duke University School of Medicine, 2301 Erwin Rd, Durham, NC 27710.. Electronic address: julian.hertz@duke.edu.
Francis M SakitaKilimanjaro Christian Medical Centre, PO Box 3010, Moshi, Tanzania; Kilimanjaro Christian Medical University College, PO Box 3010, Moshi, Tanzania.
Godfrey L KwekaKilimanjaro Christian Medical Centre, PO Box 3010, Moshi, Tanzania; Kilimanjaro Christian Research Institute, PO Box 2236, Moshi, Tanzania.
Alexander T LimkakengDivision of Emergency Medicine, Duke University School of Medicine, 2301 Erwin Rd, Durham, NC.
Sophie W GalsonDivision of Emergency Medicine, Duke University School of Medicine, 2301 Erwin Rd, Durham, NC; Duke Global Health Institute, 310 Trent Drive, Durham, NC.
Jinny J YeDivision of Emergency Medicine, Duke University School of Medicine, 2301 Erwin Rd, Durham, NC.
Tumsifu G TarimoKilimanjaro Christian Medical Centre, PO Box 3010, Moshi, Tanzania; Kilimanjaro Christian Research Institute, PO Box 2236, Moshi, Tanzania.
Gloria TemuKilimanjaro Christian Medical Centre, PO Box 3010, Moshi, Tanzania; Kilimanjaro Christian Medical University College, PO Box 3010, Moshi, Tanzania.
Nathan M ThielmanDuke Global Health Institute, 310 Trent Drive, Durham, NC; Department of Internal Medicine, Duke University School of Medicine, 2301 Erwin Rd, Durham, NC.
Janet P BettgerDuke Global Health Institute, 310 Trent Drive, Durham, NC; Department of Orthopaedic Surgery, Duke University School of Medicine, 200 Trent Dr, Durham, NC; Duke Clinical Research Institute, 300 W Morgan St, Durham, NC.
John A BartlettDuke Global Health Institute, 310 Trent Drive, Durham, NC; Kilimanjaro Christian Medical Centre, PO Box 3010, Moshi, Tanzania; Department of Internal Medicine, Duke University School of Medicine, 2301 Erwin Rd, Durham, NC.
Blandina T MmbagaKilimanjaro Christian Medical Centre, PO Box 3010, Moshi, Tanzania; Kilimanjaro Christian Research Institute, PO Box 2236, Moshi, Tanzania; Kilimanjaro Christian Medical University College, PO Box 3010, Moshi, Tanzania.
Gerald S BloomfieldDuke Global Health Institute, 310 Trent Drive, Durham, NC; Division of Cardiology, Duke University School of Medicine, 2301 Erwin Rd, Durham, NC; Duke Clinical Research Institute, 300 W Morgan St, Durham, NC.

Funding

Vanderbilt-Emory-Cornell-Duke Global Health Fellowship Consortium-Expanding Diversity for Global Equity (EDGE)D43TW009337 · FIC · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ALIYU, MUKTAR HASSAN, HEIMBURGER, DOUGLAS CORBETT · 2017 to 2021
$6.3M
FIC NIH HHS D43 TW009337
6 · The paper itself

Abstract

backgroundGrowing evidence suggests that under-diagnosis of acute myocardial infarction (AMI) may be common in sub-Saharan Africa. Prospective studies of routine AMI screening among patients presenting to emergency departments in sub-Saharan Africa are lacking. Our objective was to determine the prevalence of AMI among patients in a Tanzanian emergency department.

methodsIn a prospective observational study, consecutive adult patients presenting with chest pain or shortness of breath to a referral hospital emergency department in northern Tanzania were enrolled. Electrocardiogram (ECG) and troponin testing were performed for all participants to diagnose AMI types according to the Fourth Universal Definition. All ECGs were interpreted by two independent physician judges. ECGs suggesting ST-elevation myocardial infarction (STEMI) were further reviewed by additional judges. Mortality was assessed 30 days following enrollment.

resultsOf 681 enrolled participants, 152 (22.3%) had AMI, including 61 STEMIs and 91 non-STEMIS (NSTEMIs). Of AMI patients, 91 (59.9%) were male, mean (SD) age was 61.2 (18.5) years, and mean (SD) duration of symptoms prior to presentation was 6.6 (12.2) days. In the emergency department, 35 (23.0%) AMI patients received aspirin and none received thrombolytics. Of 150 (98.7%) AMI patients completing 30-day follow-up, 65 (43.3%) had died.

conclusionsIn a northern Tanzanian emergency department, AMI is common, rarely treated with evidence-based therapies, and associated with high mortality. Interventions are needed to improve AMI diagnosis, care, and outcomes.

Indexed as

AdultAgedEmergency Service, HospitalFemaleHumansMaleMiddle AgedMyocardial InfarctionPrevalenceProspective StudiesTanzania

Identifiers

PMID32619815
PMCPMC7442678

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.