Evidence map›Paper›PMID 32619711›Full record

ArticleNeuroImage2020

Cortical and subcortical functional specificity associated with response inhibition.

Leah Maizey, C John Evans, Nils Muhlert, Frederick Verbruggen, Christopher D Chambers, Christopher P G Allen

Open access · goldAbstract read
In one paragraph

Article in NeuroImage, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 30 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Leah MaizeyCardiff University Brain Research Imaging Centre, School of Psychology, Cardiff University, United Kingdom. Electronic address: maizeylm@cardiff.ac.uk.
C John EvansCardiff University Brain Research Imaging Centre, School of Psychology, Cardiff University, United Kingdom.
Nils MuhlertDivision of Neuroscience and Experimental Psychology, University of Manchester, United Kingdom.
Frederick VerbruggenDepartment of Experimental Psychology, Ghent University, Belgium.
Christopher D ChambersCardiff University Brain Research Imaging Centre, School of Psychology, Cardiff University, United Kingdom.
Christopher P G AllenCardiff University Brain Research Imaging Centre, School of Psychology, Cardiff University, United Kingdom. Electronic address: allencp@cardiff.ac.uk.
Cardiff University · GBGhent University · BEUniversity of Manchester · GB

Funding

Biotechnology and Biological Sciences Research Council BB/K008277/1Wellcome Trust 104943/Z/15/Z
6 · The paper itself

Abstract

Is motor response inhibition supported by a specialised neuronal inhibitory control mechanism, or by a more general system of action updating? This pre-registered study employed a context-cueing paradigm requiring both inhibitory and non-inhibitory action updating in combination with functional magnetic resonance imaging to test the specificity of responses under different updating conditions, including the cancellation of actions. Cortical regions of activity were found to be common to multiple forms of action updating. However, functional specificity during response inhibition was observed in the anterior right inferior frontal gyrus. In addition, fronto-subcortical activity was explored using a novel contrast method. These exploratory results indicate that the specificity for response inhibition observed in right prefrontal cortex continued downstream and was observed in right hemisphere subcortical activity, while left hemisphere activity was associated with right-hand response execution. Overall, our findings reveal both common and distinct correlates of response inhibition in prefrontal cortex, with exploratory analyses supporting putative models of subcortical pathways and extending them through the demonstration of lateralisation.

Indexed as

Inhibition, PsychologicalAdolescentAdultBasal GangliaBrain MappingCerebral CortexExecutive FunctionFemaleFunctional LateralityHumansMagnetic Resonance ImagingMalePsychomotor PerformanceYoung AdultAction controlAction pathwaysAction updatingBasal gangliaResponse executionResponse inhibition

Identifiers

PMID32619711
PMCPMC7573537
OpenAlexW3040212938

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.