Trial reportInternational journal of psychophysiology : official journal of the International Organization of Psychophysiology2020
Acute psychological stress, autonomic function, and arterial stiffness among women.
Trial report in International journal of psychophysiology : official journal of the International Organization of Psychophysiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- Acute Psychological Stress and Pulse Wave Velocity: Meta-Analysis and Recommendations for Future Research.Psychophysiology · 2025Pooled it
- Article
- From protection to predisposition: A narrative review of sex-specific vascular responses to acute stressors across the lifespan.Physiological reports · 2026Review
- Mindfulness-based intervention alters nonlinear heart rate variability in a pilot study.Discover mental health · 2026Article
- Reliability of Handheld Ultrasound Assessment of Brachial Artery Flow-Mediated Dilation Using AI-Assisted Automated Analysis in Postmenopausal Women.Medicina (Kaunas, Lithuania) · 2026Article
- Arterial stiffness in the context of heart rate and vasomotion during orthostatic stress and cognitive load.Frontiers in network physiology · 2026Article
- Arterial stiffness and vascular aging: mechanisms, prevention, and therapy.Signal transduction and targeted therapy · 2025Review
- Longitudinal dynamics of pulse wave velocity in the days after acute ischaemic stroke: prospective cohort study.BMJ open · 2025Observational
- Perceived stress is associated with impaired artery elasticity: An observational study from the Vara- Skövde cohort.PloS one · 2025Observational
- Association between arterial stiffness, stress and depression among undergraduate medical students in India.Bioinformation · 2025Article
- The correlation between mental health and arterial stiffness in Chinese population.Scientific reports · 2024Article
- The associations of depressive symptoms and perceived stress with arterial health in adolescents.Physiological reports · 2024Article
- Vascular function in hypertension: does gender dimension matter?Journal of human hypertension · 2023Review
- Association of Physical, Psychological and Psychosocial Attributes With Arterial Stiffness in Cardiovascular Disorders: A Systematic Literature Review.Journal of lifestyle medicine · 2023Review
- Heart Rate Variability for Evaluating Psychological Stress Changes in Healthy Adults: A Scoping Review.Neuropsychobiology · 2023Article
- A Workcation Improves Cardiac Parasympathetic Function during Sleep to Decrease Arterial Stiffness in Workers.Healthcare (Basel, Switzerland) · 2022Article
- The independent association between salivary alpha-amylase activity and arterial stiffness in Japanese men and women: the Toon Health Study.Hypertension research : official journal of the Japanese Society of Hypertension · 2022Article
- Pulse Wave Velocity, a Predictor of Major Adverse Cardiovascular Events, and Its Correlation with the General Stress Level of Health Care Workers during the COVID-19 Pandemic.Medicina (Kaunas, Lithuania) · 2022Article
- Genome-Wide mRNA Expression Analysis of Acute Psychological Stress Responses.MEDICC review · 2022Article
- Three-minute bench step exercise as a countermeasure for acute mental stress-induced arterial stiffening.PloS one · 2022Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
This study aimed to investigate the effect of acute psychological stress on autonomic function and arterial stiffness, and to test a mediating role of changes in autonomic function between acute stress and arterial stiffness. Eighty-five healthy female adults were randomized into either an experimental or control group. The Trier Social Stress Test (TSST) was used to induce acute psychological stress. Autonomic function (measured by pre-ejection period [PEP] from cardiac impedance and high frequency [HF] of heart rate variability [HRV]) and arterial stiffness (measured by carotid and femoral pulse wave velocity [cfPWV] and augmentation index [AIx]) were assessed before and after the TSST. The mean age of the participants was 28.78 (±9.84) years old. Experimental group participants had a significant increase in cfPWV (p = .025) and AIx (p = .017) following the stressor, compared with those in the control group, after controlling for age, body mass index, and systolic blood pressure. However, no significant group differences were observed in changes in PEP (p = .181) and HF (p = .058). Changes in PEP and HF were neither associated with changes in cfPWV (p = .975 and p = .654, respectively), nor in AIx (p = .376 and p = .323, respectively). The results suggest that even a brief period of mild to moderate stress, which does not cause sustainable changes in autonomic function, may still exert significant adverse effects on arterial stiffness. The changes in arterial stiffness were not related to changes in autonomic function. Future experimental studies with several measurement points are recommended to identify distinct effects of stress on autonomic function and arterial stiffness.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.