Observational studyCritical care medicine2020
Evaluating the Clinical Impact of Rapid Response Electroencephalography: The DECIDE Multicenter Prospective Observational Clinical Study.
Observational study in Critical care medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
43 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Guidelines for Seizure Prophylaxis in Patients Hospitalized with Nontraumatic Intracerebral Hemorrhage: A Clinical Practice Guideline for Health Care Professionals from the Neurocritical Care Society.Neurocritical care · 2025Guideline
- Noninvasive mobile EEG as a tool for seizure monitoring and management: A systematic review.Epilepsia · 2022Pooled it
- Educational initiatives for electroencephalography in the critical care setting: a systematic review and meta-analysis.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2021Pooled it
- Early Neurologic Recovery, Practice Pattern Variation, and the Risk of Endotracheal Intubation Following Established Status Epilepticus.Neurology · 2021Trial
- Article
- Article
- Point-of-Care EEG Artificial Intelligence Measure of Seizure Burden Associates With Clinical Outcome at Discharge.Critical care medicine · 2026Article
- Scalable biomarkers of Parkinson's disease: insights from mobile EEG in Peru.Scientific reports · 2026Article
- EEG for bedside monitoring: the intensivist's point of view.Critical care (London, England) · 2026Review
- Arterial spin labeling imaging of epileptic seizures with and without status epilepticus: A descriptive study.Acta neurologica Belgica · 2026Article
- Point-of-Care EEG for Non-Convulsive Seizure and Status Epilepticus: Advances, Limitations, and Future Directions.Journal of clinical medicine · 2026Review
- Point-of-care electroencephalography for prediction of postoperative delirium in older adults undergoing elective surgery: protocol for a prospective cohort study.Biology methods & protocols · 2026Review
- Ensuring Access to Neurologic Care: Challenges and Opportunities.Seminars in neurology · 2025Review
- Automated detection of interictal epileptiform discharges with few electroencephalographic channels.Epilepsia · 2025Article
- Point-of-Care Electroencephalography in Acute Neurological Care: A Narrative Review.Neurology international · 2025Review
- Evaluating the Impact of Point-of-Care Electroencephalography on Length of Stay in the Intensive Care Unit: Subanalysis of the SAFER-EEG Trial.Neurocritical care · 2025Article
- Rapid response electroencephalography decreases time to seizure diagnosis in pediatric acute care patients.Epilepsia open · 2025Observational
- The Role of Artificial Intelligence in the Diagnosis and Management of Non-convulsive Seizures: A Narrative Review.Cureus · 2025Review
- Correlation between lateralized periodic discharges and arterial spin labeling perfusion imaging in patients with status epilepticus.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024Article
- Evaluating the feasibility of prehospital point-of-care EEG: The prehospital implementation of rapid EEG (PHIRE) study.Journal of the American College of Emergency Physicians open · 2024Article
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Authors and funding
12 authors.
Funding
Abstract
objectivesTo measure the diagnostic accuracy, timeliness, and ease of use of Ceribell rapid response electroencephalography. We assessed physicians' diagnostic assessments and treatment plans before and after rapid response electroencephalography assessment. Primary outcomes were changes in physicians' diagnostic and therapeutic decision making and their confidence in these decisions based on the use of the rapid response electroencephalography system. Secondary outcomes were time to electroencephalography, setup time, ease of use, and quality of electroencephalography data.
designProspective multicenter nonrandomized observational study.
settingICUs in five academic hospitals in the United States. SUBJECTS: Patients with encephalopathy suspected of having nonconvulsive seizures and physicians evaluating these patients.
interventionsPhysician bedside assessment of sonified electroencephalography (30 s from each hemisphere) and visual electroencephalography (60 s) using rapid response electroencephalography. MEASUREMENTS AND MAIN
resultsPhysicians (29 fellows or residents, eight attending neurologists) evaluated 181 ICU patients; complete clinical and electroencephalography data were available in 164 patients (average 58.6 ± 18.7 yr old, 45% females). Relying on rapid response electroencephalography information at the bedside improved the sensitivity (95% CI) of physicians' seizure diagnosis from 77.8% (40.0%, 97.2%) to 100% (66.4%, 100%) and the specificity (95% CI) of their diagnosis from 63.9% (55.8%, 71.4%) to 89% (83.0%, 93.5%). Physicians' confidence in their own diagnosis and treatment plan were also improved. Time to electroencephalography (median [interquartile range]) was 5 minutes (4-10 min) with rapid response electroencephalography while the conventional electroencephalography was delayed by several hours (median [interquartile range] delay = 239 minutes [134-471 min] [p < 0.0001 using Wilcoxon signed rank test]). The device was rated as easy to use (mean ± SD: 4.7 ± 0.6 [1 = difficult, 5 = easy]) and was without serious adverse effects.
conclusionsRapid response electroencephalography enabled timely and more accurate assessment of patients in the critical care setting. The use of rapid response electroencephalography may be clinically beneficial in the assessment of patients with high suspicion for nonconvulsive seizures and status epilepticus.
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