Evidence map›Paper›PMID 32618575›Full record

ArticleJMIR medical informatics2020

Predicting Current Glycated Hemoglobin Levels in Adults From Electronic Health Records: Validation of Multiple Logistic Regression Algorithm.

Zakhriya Alhassan, David Budgen, Riyad Alshammari, Noura Al Moubayed

Abstract read
In one paragraph

Article in JMIR medical informatics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Inference for the Case Probability in High-dimensional Logistic Regression.Journal of machine learning research : JMLR · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Zakhriya AlhassanDepartment of Computer Science, Durham University, Durham, United Kingdom.ORCID https://orcid.org/0000-0002-6644-1656
David BudgenDepartment of Computer Science, Durham University, Durham, United Kingdom.ORCID https://orcid.org/0000-0001-7143-0241
Riyad AlshammariCollege of Public Health and Health Informatics, Health Informatics Department, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.ORCID https://orcid.org/0000-0002-0529-2458
Noura Al MoubayedDepartment of Computer Science, Durham University, Durham, United Kingdom.ORCID https://orcid.org/0000-0001-8942-355X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundElectronic health record (EHR) systems generate large datasets that can significantly enrich the development of medical predictive models. Several attempts have been made to investigate the effect of glycated hemoglobin (HbA

objectiveThe aim of this study is to perform a replication study to validate, evaluate, and identify the strengths and weaknesses of replicating a predictive model that employed multiple logistic regression with EHR data to forecast the levels of HbA

methodsA total of 3 models were developed and compared with the model created in the original study. The models were trained and tested using a larger dataset from Saudi Arabia with 36,378 records. The 10-fold cross-validation approach was used for measuring the performance of the models.

resultsApplying the method employed in the original study achieved an accuracy of 74% to 75% when using the dataset collected from Saudi Arabia, compared with 77% obtained from using the population from the United States. The results also show a different ranking of importance for the predictors between the original study and the replication. The order of importance for the predictors with our population, from the most to the least importance, is age, random blood sugar, estimated glomerular filtration rate, total cholesterol, non-high-density lipoprotein, and body mass index.

conclusionsThis replication study shows that direct use of the models (calculators) created using multiple logistic regression to predict the level of HbA

Indexed as

diabetesdifferentiated replicationEHRelectronic health recordsglycated hemoglobinHbA1chemoglobinlogistic regressionmedical informaticsprediction

Identifiers

PMID32618575
PMCPMC7367516

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.