Evidence map›Paper›PMID 32618494›Full record

ArticleGut microbes2020

Hemolysin BL from novel

Jiajia Chen, Shoukui Hu, Dengbo Ji, Zhaoya Gao, Hanyang Wang, Yong Yang, Yongkang Chen, Jin Gu

Open access · goldAbstract read
In one paragraph

Article in Gut microbes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Microbial metabolites: cause or consequence in gastrointestinal disease?American journal of physiology. Gastrointestinal and liver physiology · 2022
    Review
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Jiajia ChenKey Laboratory of Carcinogenesis and Translational Research, Ministry of Education, Peking University Cancer Hospital & Institute , Beijing, China.ORCID 0000-0002-5363-1389
Shoukui HuDepartment of Gastrointestinal Surgery, Peking University Shougang Hospital , Beijing, China.
Dengbo JiKey Laboratory of Carcinogenesis and Translational Research, Ministry of Education, Peking University Cancer Hospital & Institute , Beijing, China.
Zhaoya GaoDepartment of Gastrointestinal Surgery, Peking University Shougang Hospital , Beijing, China.ORCID 0000-0002-0874-2266
Hanyang WangKey Laboratory of Carcinogenesis and Translational Research, Ministry of Education, Peking University Cancer Hospital & Institute , Beijing, China.
Yong YangKey Laboratory of Carcinogenesis and Translational Research, Ministry of Education, Peking University Cancer Hospital & Institute , Beijing, China.
Yongkang ChenKey Laboratory of Carcinogenesis and Translational Research, Ministry of Education, Peking University Cancer Hospital & Institute , Beijing, China.
Jin GuKey Laboratory of Carcinogenesis and Translational Research, Ministry of Education, Peking University Cancer Hospital & Institute , Beijing, China.
Peking University · CNPeking University Shougang Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The gut microbiota plays an important role in cancer development and immunotherapy. Bacterial toxins have enormous antitumor potential due to their cytotoxicity and ability to activate the immune system. Using 16S rRNA gene sequencing, we compared the gut microbiota composition of fecal samples from healthy individuals and patients with colorectal cancer (CRC) and observed that the

Indexed as

A549 CellsAnimalsAntineoplastic AgentsBacillusBacterial ProteinsCell Line, TumorCell MembraneCell ProliferationColorectal NeoplasmsCulture Media, ConditionedFemaleGastrointestinal MicrobiomeHCT116 CellsHeLa CellsHemolysin ProteinsHumansAntineoplastic AgentsBacterial ProteinsCulture Media, Conditionedhemolysin BL protein, BacillusHemolysin ProteinsRNA, Ribosomal, 16Santitumor activityBacillus toyonensis BV-17colorectal cancerGut microbiotahemolysin BL

Identifiers

PMID32618494
PMCPMC7524337
OpenAlexW3038156522

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.