Evidence map›Paper›PMID 32618481›Full record

ArticleCurrent eye research2021

A Comparison of Applanation and Rebound Tonometers in Young Chicks.

Lisa A Ostrin, Christine F Wildsoet

Open access · greenAbstract readComparative Study
In one paragraph

Article in Current eye research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 9 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Lisa A OstrinCollege of Optometry, University of Houston , Houston, Texas, USA.
Christine F WildsoetSchool of Optometry and Vision Science Program, University of California Berkeley , Berkeley, California, USA.ORCID 0000-0003-2671-2391
University of California, Berkeley · USUniversity of Houston · US

Funding

Mechanisms underlying emmetropization and local eye growth regulationR01EY012392 · NEI · UNIVERSITY OF CALIFORNIA BERKELEY · PI WILDSOET, CHRISTINE FRANCES · 1999 to 2018
$4.6M
Structural and Functional Changes in Myopia and Susceptibility to GlaucomaK08EY022696 · NEI · UNIVERSITY OF HOUSTON · PI OSTRIN, LISA A · 2012 to 2016
$826k
NEI NIH HHS K08 EY022696NEI NIH HHS R01 EY012392
6 · The paper itself

Abstract

purposeTo assess the validity of and compare applanation and rebound tonometry readings of intraocular pressure in alert normal chicks from ages 3 to 45 days.

methodsIntraocular pressures (IOPs) were measured weekly in awake White Leghorn chicks, from ages 3-45 days (n = 22-30 per age group), with both applanation Tono-Pen and rebound TonoLab tonometers. Three repeated measurements on individual eyes were used to derive variance data for both instruments at each age. Calibration curves were also derived for each instrument and each age, weekly from ages 10-45 days (n = 3-4 per age group), from

resultsThe TonoLab showed less within measurement variability, but more variability with age, than the Tono-Pen. The coefficient of variation ranged from 3.8-8.3% for the TonoLab, compared to 11.0-19.7% for the Tono-Pen across all ages. For the youngest, 3 day-old chicks, mean IOPs recorded with the Tono-Pen and TonoLab were not significantly different (17.0 ± 5.6 and 15.2 ± 3.7 mmHg, respectively,

conclusionsBoth the Tono-Pen and TonoLab gave IOP readings that differed from manometry settings in normal young chicks over some or all of the ages tested. These results reinforce the importance of calibrating clinical tonometers in animal studies involving IOP as a key variable.

Indexed as

AnimalsAnimals, NewbornChickensEyeIntraocular PressureModels, AnimalTonometry, Ocularanimal modelapplanation tonometryChickchickenrebound tonometry

Identifiers

PMID32618481
PMCPMC7779666
OpenAlexW3038961652

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.