Evidence map›Paper›PMID 32618243›Full record

Observational studyThe American journal of tropical medicine and hygiene2020

Predictors of Loss to Follow-Up among Men with Tuberculosis in Puducherry and Tamil Nadu, India.

Thomas J Zhou, Subitha Lakshminarayanan, Sonali Sarkar, Selby Knudsen, C Robert Horsburgh, Muthuraj Muthaiah, Carolyn K Kan, Padmini Salgame, Jerrold J Ellner, Gautam Roy and 2 more

Open access · hybridAbstract readObservational Study
In one paragraph

Observational study in The American journal of tropical medicine and hygiene, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 3 pooled it
0.3field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 3 syntheses or guidelines pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Observational
  7. Impact of Undernutrition on Tuberculosis Treatment Outcomes in India: A Multicenter, Prospective, Cohort Analysis.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Thomas J Zhou1Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts.
Subitha Lakshminarayanan2Department of Preventive and Social Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.
Sonali Sarkar2Department of Preventive and Social Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.
Selby Knudsen3Department of Medicine, Section of Infectious Diseases, Boston University School of Medicine, Boston, Massachusetts.
C Robert Horsburgh1Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts.
Muthuraj Muthaiah5Intermediate Reference Laboratory, Government Hospital for Chest Diseases, Puducherry, India.
Carolyn K Kan6Department of Medicine, Boston University School of Medicine, Boston, Massachusetts.
Padmini Salgame7Department of Medicine, Rutgers New Jersey Medical School, Newark, New Jersey.
Jerrold J Ellner7Department of Medicine, Rutgers New Jersey Medical School, Newark, New Jersey.
Gautam Roy2Department of Preventive and Social Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.
Helen E Jenkins1Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts.
Natasha S Hochberg3Department of Medicine, Section of Infectious Diseases, Boston University School of Medicine, Boston, Massachusetts.
Boston University · USJawaharlal Institute of Post Graduate Medical Education and Research · INRutgers, The State University of New Jersey · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Identifying predictors of loss to follow-up (LTFU; treatment lapse ≥ 2 months) among people with tuberculosis (TB) may assist programmatic efforts in controlling the spread of TB. Newly diagnosed smear-positive TB patients were enrolled in the Regional Prospective Observational Research for TB study in Puducherry and Tamil Nadu, India. Treatment records were used to identify LTFU of those who were enrolled from May 2014 through December 2017. This nested case-control study evaluated male TB patients. Predictors were assessed using multivariable logistic regression. Of 425 men with TB, 82 (19%) were LTFU. In the adjusted analyses of males, divorced/separated marital status (adjusted odds ratio [aOR] 3.80; 95% CI: 1.39-10.38) and at-risk alcohol use (aOR 1.92; 95% CI: 1.12-3.27) were significant predictors for increased risk of LTFU, and diabetes was a significant predictor for decreased risk of LTFU (aOR 0.52; 95% CI: 0.29-0.92). Of 53 men with recorded date of last treatment visit, 23 (43%) and 43 (81%) had LTFU within the first 2 and first 4 months of treatment, respectively. Addressing at-risk alcohol use and providing more intensive follow-up could lead to improved treatment completion.

Indexed as

Lost to Follow-UpAdultAlcohol DrinkingAntitubercular AgentsCase-Control StudiesFemaleFollow-Up StudiesHumansIndiaLogistic ModelsMaleMarital StatusMiddle AgedMycobacterium tuberculosisRisk FactorsTuberculosis, PulmonaryAntitubercular Agents

Identifiers

PMID32618243
PMCPMC7470548
OpenAlexW3038385689

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.