ArticleJournal of magnetic resonance imaging : JMRI2020
Determination of Brain Metabolite T
Article in Journal of magnetic resonance imaging : JMRI, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 5 citations in OpenAlex.
- The Goldilocks Zone for 3-T MRS Studies Using Semi-LASER: Determining the Optimal Balance Between Repetition Time and Scan Time.NMR in biomedicine · 2025Article
- Accelerated 3D metabolite TMagnetic resonance in medicine · 2024Article
- The future is 2D: spectral-temporal fitting of dynamic MRS data provides exponential gains in precision over conventional approaches.Magnetic resonance in medicine · 2023Article
- Inter-subject stability and regional concentration estimates of 3D-FID-MRSI in the human brain at 7 T.NMR in biomedicine · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
backgroundJ-coupled metabolites are often measured at a predetermined echo time in the presence of macromolecule signals, which complicates the measurement of metabolite T PURPOSE: To evaluate the feasibility and benefits of measuring metabolite T STUDY TYPE: Prospective. SUBJECTS: Five healthy volunteers (three females and two males; age = 27 ± 7 years). FIELD STRENGTH/SEQUENCE: 7T scanner using a point resolved spectroscopy (PRESS)-based spectral editing MR spectroscopy (MRS) sequence with inversion recovery (IR). ASSESSMENT: F-tests were performed to evaluate if the new approach, which fitted all the spectra together and used the same baselines for the three different IR settings, significantly reduced the variances of the metabolite T STATISTICAL TESTS: Cramer-Rao lower bound (CRLB), within-subject coefficient of variation, and F-test.
resultsThe T DATA
conclusionKeeping macromolecule signals intact by using only long IR times allowed the use of a single macromolecule spectral model for different IR settings and significantly reduced the variances of NAA, Glu, Gln, tCr, tCho, and mI T LEVEL OF EVIDENCE: 1 TECHNICAL EFFICACY STAGE: 1.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.