Evidence map›Paper›PMID 32617889›Full record

ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2020

Health-related quality of life of women after HPV testing as triage strategy for an abnormal Pap smear: a nested randomized pragmatic trial in a middle-income country.

Yenny Urrea Cosme, Verónica Córdoba Sánchez, Gloria I Sánchez, Armando Baena, Mario Alberto Ruiz Osorio, David Rodríguez Zabala, Isabel C Garcés-Palacio

Registry-linked trialAbstract read
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In one paragraph

Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02067468 (Evaluation of Strategies for Optimal Clinical Management of Women With Atypical Squamous Cells of Undetermined Significance), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02067468 nacompletednot on this map

Evaluation of Strategies for Optimal Clinical Management of Women With Atypical Squamous Cells of Undetermined Significance (ASC-US)

TypeinterventionalSponsorUniversidad de AntioquiaRan2011 to 2016Enrolled2,661ConditionsCervical Abnormalities, Cervical Intraepithelial Neoplasia Grade 2/3, Cervical CancerArmsHPV test, COLPOSCOPY, cytology
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Yenny Urrea CosmeGrupo Atropos, Universidad de Antioquia UdeA, Calle 70 No. 52-21, Medellín, Colombia.
Verónica Córdoba SánchezGrupo Atropos, Universidad de Antioquia UdeA, Calle 70 No. 52-21, Medellín, Colombia.
Gloria I SánchezGrupo Infección y Cáncer, Facultad de Medicina, Universidad de Antioquia UdeA, Calle 70 No. 52-21, Medellín, Colombia.
Armando BaenaPrevention and Implementation Group, International Agency for Research on Cancer / World Health Organization (IARC/WHO), 150 Cours Albert Thomas, 69372, Lyon Cedex 08, France.
Mario Alberto Ruiz OsorioGrupo Atropos, Universidad de Antioquia UdeA, Calle 70 No. 52-21, Medellín, Colombia.
David Rodríguez ZabalaGrupo Atropos, Universidad de Antioquia UdeA, Calle 70 No. 52-21, Medellín, Colombia.
Isabel C Garcés-PalacioGrupo de Epidemiología, Facultad Nacional de Salud Pública, Universidad de Antioquia UdeA, Calle 70 No. 52-21, Medellín, Colombia. icristina.garces@udea.edu.co.ORCID http://orcid.org/0000-0003-0531-276X
Universidad de Antioquia · COCentre international de recherche sur le cancer · FR

Funding

World Health Organization 001
6 · The paper itself

Abstract

backgroundInformation obtained in studies on the impact of human papilloma virus (HPV) testing on health-related quality of life is contradictory.

objectiveTo assess the impact on health-related quality of life of the HPV test, colposcopy, and cytology as triage strategies after a cytology with atypical squamous cells of undetermined significance (ASCUS) in Medellín, Colombia.

methodsWe carried out a nested analysis on the randomized pragmatic trial (ASCUS-COL). Women with ASCUS were assigned randomly to one of the 3 arms (Pap smear, colposcopy, HPV). Participants completed a questionnaire at baseline, two weeks after receiving the results of the triage tests and one year after the second questionnaire. We used the SF-36 to assess health-related quality of life.

resultsThe sum score of the physical health component (PHC) and mental health component (MHC) increased significantly over time for the whole sample and there were no statistically significant differences between arms of PHC = survey 1: mean 52.4 (SD 8.21) vs. survey 3: mean 54.4 (SD 8.16) p < 0.0001 and of MHC = survey 1: mean 44.9 (SD 11.72) vs. survey 3: mean 48.1 (SD 11.20) p < 0.0001. A lower MHC occurred in women with lesser schooling, belonging to the public health care regimen, higher number of live births, and separated. A lower PHC was associated with the cytology arm, higher age, lesser schooling, and belonging to the subsidized regime. The risk of having depression went from 42% in the first survey to 26% in the third.

conclusionThe triage strategies affected health-related quality of life in the same manner. ClinicalTrials.gov Identifier: NCT02067468.

Indexed as

AdultFemaleHumansMiddle AgedPapanicolaou TestPapillomaviridaePapillomavirus InfectionsQuality of LifeTriageYoung AdultAtypical squamous cells of undetermined significance (ASCUS)Health-related quality of life (HRQoL)Human papilloma virus (HPV)

Identifiers

PMID32617889
OpenAlexW3040633248

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.