Evidence map›Paper›PMID 32617856›Full record

ArticleGlycoconjugate journal2020

Structural characteristics and anti-complement activities of polysaccharides from Sargassum hemiphyllum.

Weihua Jin, Qiufu Fang, Di Jiang, Tongtong Li, Bin Wei, Jiadong Sun, Wenjing Zhang, Zhongshan Zhang, Fuming Zhang, Robert J Linhardt and 2 more

Abstract read
PubMed Publisher
In one paragraph

Article in Glycoconjugate journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 2 countries.

Weihua JinCollege of Biotechnology and Bioengineering, Zhejiang University of Technology, 310014, Hangzhou, China.
Qiufu FangCollege of Biotechnology and Bioengineering, Zhejiang University of Technology, 310014, Hangzhou, China.
Di JiangCollege of Biotechnology and Bioengineering, Zhejiang University of Technology, 310014, Hangzhou, China.
Tongtong LiCollege of Biotechnology and Bioengineering, Zhejiang University of Technology, 310014, Hangzhou, China.
Bin WeiCollaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, College of Pharmaceutical Sciences, Zhejiang University of Technology, 310014, Hangzhou, China.
Jiadong SunDepartment of Biomedical and Pharmaceutical Sciences, College of Pharmacy, University of Rhode Island, 02881, Kingston, RI, USA.
Wenjing ZhangDepartment of Endocrinology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, 310016, Hangzhou, China.
Zhongshan ZhangKey Laboratory of Vector Biology and Pathogen Control of Zhejiang Province, Huzhou University, 313000, Huzhou, China.
Fuming ZhangDepartment of Chemical and Biological Engineering, Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, NY, 12180, USA.
Robert J LinhardtDepartment of Chemical and Biological Engineering, Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, NY, 12180, USA.
Hong WangCollaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, College of Pharmaceutical Sciences, Zhejiang University of Technology, 310014, Hangzhou, China. hongw@zjut.edu.cn.
Weihong ZhongCollege of Biotechnology and Bioengineering, Zhejiang University of Technology, 310014, Hangzhou, China. whzhong@zjut.edu.cn.
Zhejiang University of Technology · CNRensselaer Polytechnic Institute · USHuzhou University · CNUniversity of Rhode Island · USZhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Three polysaccharides (SH-1, SH-2 and SH-3) were purified from a brown macroalgea, Sargassum hemiphyllum. The autohydrolysis products from each polysaccharide were separated to three fractions (S fractions as oligomers, L fractions as low molecular weight polysaccharides and H fractions as high molecular weight polysaccharides). Mass spectroscopy of S fractions (SH-1-S, SH-2-S and SH-3-S) showed that these three polymers all contained short stretches of sulfated fucose. The structures of L fractions (SH-1-L, SH-2-L and SH-3-L) were determined by nuclear magnetic resonance (NMR). SH-1-L was composed of two units, unit A (sulfated galactofucan) and unit B (sulfated xylo-glucuronomannan). Unit A contained a backbone of (1, 6-linked β-D-Gal) n

Indexed as

FucoseGalactoseGlucuronic AcidHydrolysisMagnetic Resonance SpectroscopyMass SpectrometryPolysaccharidesSargassumFucosegalactofucanGalactoseGlucuronic AcidPolysaccharidesAnticomplement activityFucoidanSargassum hemiphyllumSulfated galactofucanSulfated galacto-fuco-xylo-glucuronomannan

Identifiers

PMID32617856
OpenAlexW3039344389

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.