Evidence map›Paper›PMID 32617654›Full record

ArticlePflugers Archiv : European journal of physiology2020

Roles of glutamate and GABA of the Kölliker-Fuse nucleus in generating the cardiovascular chemoreflex.

Nafiseh Mirzaei-Damabi, Masoumeh Hatam, Fahimeh Yeganeh, Farzaneh Ketabchi, Ali Nasimi

Abstract read
PubMed Publisher
In one paragraph

Article in Pflugers Archiv : European journal of physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Nafiseh Mirzaei-DamabiDepartment of Physiology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.ORCID 0000-0002-4221-0714
Masoumeh HatamDepartment of Physiology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran. mahatam@sums.ac.ir.ORCID 0000-0001-8139-5232
Fahimeh YeganehDepartment of Physiology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Farzaneh KetabchiDepartment of Physiology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Ali NasimiDepartment of Physiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Shiraz University of Medical Sciences · IRIsfahan University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Kölliker-Fuse (KF) nucleus is a part of the parabrachial complex, located in the dorsolateral pons. It is involved in the chemoreflex-evoked cardiovascular and respiratory changes, but the role of GABA and glutamate in cardiovascular chemoreflex has not been shown yet. This study was performed to determine the role of GABA, glutamate, and their interaction in the KF, in cardiovascular chemoreflex in anesthetized rat. The antagonists were microinjected into the KF, and arterial pressure, heart rate, and single-unit responses were recorded simultaneously. The chemoreflex was evoked by i.v. injection of KCN, consisted of a short pressor followed by long bradycardia responses. Both responses were significantly attenuated by injection of a synaptic blocker (CoCl

Indexed as

AnimalsBicucullineBlood PressureCardiovascular SystemChemoreceptor Cellsgamma-Aminobutyric AcidGlutamic AcidHeart RateKolliker-Fuse NucleusMalePonsRatsRats, Sprague-DawleyReceptors, AMPAReceptors, GABA-AReceptors, N-Methyl-D-AspartateBicucullinebicuculline methiodidegamma-Aminobutyric AcidGlutamic AcidReceptors, AMPAReceptors, GABA-AReceptors, N-Methyl-D-AspartateCardiovascular chemoreflexGABAGlutamateKölliker-FuseSingle-unit

Identifiers

PMID32617654
OpenAlexW3038351669

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.