Evidence map›Paper›PMID 32617641›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2020

[

Elin Pauwels, Frederik Cleeren, Térence Tshibangu, Michel Koole, Kim Serdons, Jeroen Dekervel, Eric Van Cutsem, Chris Verslype, Koen Van Laere, Guy Bormans and 1 more

3 registry-linked trialsAbstract read
PubMed Publisher
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 57 papers.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed
9.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03883776 phase1completednot on this map

Al18F-NOTA-octreotide PET Imaging of the Somatostatin Receptor in Neuroendocrine Tumors: a First-in-human PET/CT Study

TypeinterventionalSponsorUniversitaire Ziekenhuizen KU LeuvenRan2019 to 2019Enrolled12ConditionsNeuroendocrine TumorsArmsAl18F-NOTA-octreotide, PET/CT, Venous blood samples
NCT04552847 phase2 / phase3completednot on this map

Al18F-NOTA-octreotide PET Imaging of the Somatostatin Receptor in Neuroendocrine Tumors

TypeinterventionalSponsorUniversitaire Ziekenhuizen KU LeuvenRan2020 to 2022Enrolled85ConditionsNeuroendocrine TumorsArmsAl18F-NOTA-octreotide, PET/CT, PET/MR
NCT07104487 phase2recruitingnot on this mapstarted 2025, after this paper: background citation

An Exploratory Study of [18F]AlF-NOTA-octreotide PET/MRI in Carotid Artery Disease

TypeinterventionalSponsorUniversitaire Ziekenhuizen KU LeuvenRan2025 to 2029Enrolled24ConditionsStroke (CVA) or TIA, Carotid Artery Plaque, Atherosclerosis Cardiovascular Disease, Carotid ArteriosclerosisArms[18F]AlF-OC
3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 89 citations in OpenAlex.

  1. Evaluation of the safety, biodistribution, dosimetry of [European journal of nuclear medicine and molecular imaging · 2024
    Trial
  2. [European journal of nuclear medicine and molecular imaging · 2023
    Trial
  3. A prospective head-to-head comparison ofEuropean journal of nuclear medicine and molecular imaging · 2022
    Trial
  4. Growth hormone-releasing hormone, growth hormone, and neuroendocrine tumors.Journal of clinical & translational endocrinology · 2026
    Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Optimization of automated radiosynthesis method for [EJNMMI radiopharmacy and chemistry · 2026
    Article
  10. Article
  11. Head-to-Head comparison of [European journal of nuclear medicine and molecular imaging · 2026
    Article
  12. Article
  13. Head to head comparison of [European journal of nuclear medicine and molecular imaging · 2026
    Article
  14. Review
  15. Article
  16. Selective PET imaging of CXCR4 using the AlEuropean journal of nuclear medicine and molecular imaging · 2025
    Article
  17. Evaluation of [Molecular imaging and biology · 2025
    Article
  18. Observational
  19. Human dose-escalation study of PET imaging CD8European journal of nuclear medicine and molecular imaging · 2025
    Article
  20. The value ofFrontiers in medicine · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Elin PauwelsNuclear Medicine, University Hospitals Leuven, Campus Gasthuisberg, Herestraat 49, BE-3000, Leuven, Belgium.
Frederik CleerenRadiopharmaceutical Research, Department of Pharmacy and Pharmacology, KU Leuven, Leuven, Belgium.
Térence TshibanguRadiopharmaceutical Research, Department of Pharmacy and Pharmacology, KU Leuven, Leuven, Belgium.
Michel KooleNuclear Medicine, University Hospitals Leuven, Campus Gasthuisberg, Herestraat 49, BE-3000, Leuven, Belgium.
Kim SerdonsNuclear Medicine, University Hospitals Leuven, Campus Gasthuisberg, Herestraat 49, BE-3000, Leuven, Belgium.
Jeroen DekervelDigestive Oncology, University Hospitals Leuven, Leuven, Belgium.
Eric Van CutsemDigestive Oncology, University Hospitals Leuven, Leuven, Belgium.
Chris VerslypeDigestive Oncology, University Hospitals Leuven, Leuven, Belgium.
Koen Van LaereNuclear Medicine, University Hospitals Leuven, Campus Gasthuisberg, Herestraat 49, BE-3000, Leuven, Belgium.
Guy BormansRadiopharmaceutical Research, Department of Pharmacy and Pharmacology, KU Leuven, Leuven, Belgium.
Christophe M DerooseNuclear Medicine, University Hospitals Leuven, Campus Gasthuisberg, Herestraat 49, BE-3000, Leuven, Belgium. christophe.deroose@uzleuven.be.ORCID 0000-0002-6080-1577
KU Leuven · BEUniversitair Ziekenhuis Leuven · BE

Funding

Fonds Wetenschappelijk Onderzoek 12R3119NFonds Wetenschappelijk Onderzoek G0D8817N
6 · The paper itself

Abstract

purposeThe widespread use of gallium-68-labelled somatostatin analogue (SSA) PET, the current standard for somatostatin receptor (SSTR) imaging, is limited by practical and economic challenges that could be overcome by a fluorine-18-labelled alternative, such as the recently introduced [

methodsSix healthy volunteers and six NET patients with a previous clinical [

results[

conclusion[

trial registrationClinicaltrials.gov : NCT03883776, EudraCT: 2018-002827-40.

Indexed as

Neuroendocrine TumorsOctreotideGallium RadioisotopesHeterocyclic Compounds, 1-RingHumansPositron-Emission TomographyPositron Emission Tomography Computed TomographyProspective StudiesTissue Distribution1,4,7-triazacyclononane-N,N',N''-triacetic acidGallium RadioisotopesHeterocyclic Compounds, 1-RingOctreotide[18F]AlF-NOTA-octreotide[68Ga]Ga-DOTATATENeuroendocrine tumourPETSomatostatin receptor

Identifiers

PMID32617641
OpenAlexW3040371898

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.