Evidence map›Paper›PMID 32617555›Full record

ArticleThe journals of gerontology. Series A, Biological sciences and medical sciences2020

Aging, Vestibular Function, and Balance: Proceedings of a National Institute on Aging/National Institute on Deafness and Other Communication Disorders Workshop.

Yuri Agrawal, Daniel M Merfeld, Fay B Horak, Mark S Redfern, Brad Manor, Kelly P Westlake, Gay R Holstein, Paul F Smith, Tanvi Bhatt, Nicolaas I Bohnen and 1 more

Open access · greenAbstract readConference Proceedings
In one paragraph

Article in The journals of gerontology. Series A, Biological sciences and medical sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.

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  13. Walking balance recovery in people with unilateral vestibular hypofunction.Journal of vestibular research : equilibrium & orientation · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 10 institutions in 2 countries.

Yuri AgrawalDepartment of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Daniel M MerfeldDepartment of Otolaryngology-Head and Neck Surgery, Ohio State University, Columbus.
Fay B HorakDepartment of Neurology, School of Medicine, Oregon Health & Science University, Portland.
Mark S RedfernDepartment of Bioengineering, University of Pittsburgh, Pennsylvania.
Brad ManorDivision of Gerontology, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts.
Kelly P WestlakeUniversity of Maryland School of Medicine, Baltimore.
Gay R HolsteinDepartment of Neurology, Icahn School of Medicine at Mount Sinai, New York, New York.
Paul F SmithDepartment of Pharmacology and Toxicology, School of Medical Sciences, University of Otago, Dunedin, New Zealand.
Tanvi BhattDepartment of Physical Therapy, University of Illinois at Chicago.
Nicolaas I BohnenDepartment of Neurology, University of Michigan, Ann Arbor.
Lewis A LipsitzDivision of Gerontology, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts.
Beth Israel Deaconess Medical Center · USBrain Research New Zealand · NZIcahn School of Medicine at Mount Sinai · USJohns Hopkins University · USOregon Health & Science University · USThe Ohio State University · USUniversity of Illinois Chicago · USUniversity of Maryland, Baltimore · USUniversity of Michigan · USUniversity of Pittsburgh · US

Funding

Public Outreach and Education CoreP50NS091856 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MULLER, MARTIJN L. T. M. · 2014 to 2019
$10.1M
Chemical Anatomy and Synaptology of Vestibulo-Sympathetic PathwaysR01DC008846 · NIDCD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI HOLSTEIN, GAY R · 2008 to 2021
$5.8M
Does vestibular loss predict falls in patients with Alzheimer's Disease?R01AG057667 · NIA · JOHNS HOPKINS UNIVERSITY · PI OH, ESTHER SEUNGHEE · 2018 to 2022
$1.8M
Amyloidopathy, cholinopathy, dopamine responsiveness and freezing of gait in PDI01RX001631 · VA · VETERANS HEALTH ADMINISTRATION · PI BOHNEN, NICOLAAS IDA · 2016 to 2020
–
NIA NIH HHS R01 AG057667NIDCD NIH HHS R01 DC008846NINDS NIH HHS P50 NS091856RRD VA I01 RX001631
6 · The paper itself

Abstract

Balance impairment and falls are among the most prevalent and morbid conditions affecting older adults. A critical contributor to balance and gait function is the vestibular system; however, there remain substantial knowledge gaps regarding age-related vestibular loss and its contribution to balance impairment and falls in older adults. Given these knowledge gaps, the National Institute on Aging and the National Institute on Deafness and Other Communication Disorders convened a multidisciplinary workshop in April 2019 that brought together experts from a wide array of disciplines, such as vestibular physiology, neuroscience, movement science, rehabilitation, and geriatrics. The goal of the workshop was to identify key knowledge gaps on vestibular function and balance control in older adults and develop a research agenda to make substantial advancements in the field. This article provides a report of the proceedings of this workshop. Three key questions emerged from the workshop, specifically: (i) How does aging impact vestibular function?; (ii) How do we know what is the contribution of age-related vestibular impairment to an older adult's balance problem?; and more broadly, (iii) Can we develop a nosology of balance impairments in older adults that can guide clinical practice? For each of these key questions, the current knowledge is reviewed, and the critical knowledge gaps and research strategies to address them are discussed. This document outlines an ambitious 5- to 10-year research agenda for increasing knowledge related to vestibular impairment and balance control in older adults, with the ultimate goal of linking this knowledge to more effective treatment.

Indexed as

AgedAgingFemaleHumansMalePostural BalanceUnited StatesVestibular DiseasesAgingBalanceVestibular

Identifiers

PMID32617555
PMCPMC7662183
OpenAlexW3038380730

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.