Evidence map›Paper›PMID 32616797›Full record

ArticleScientific reports2020

Myopia induces meridional growth asymmetry of the retina: a pilot study using wide-field swept-source OCT.

Katharina Breher, Arne Ohlendorf, Siegfried Wahl

Abstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  7. Longitudinal measures of peripheral optical quality in young children.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2025
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  9. Impact of Genetic and Environmental Factors on Peripheral Refraction.Translational vision science & technology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Katharina BreherInstitute for Ophthalmic Research, Eberhard Karls University Tuebingen, 72076, Tübingen, Germany. katharina.breher@uni-tuebingen.de.ORCID http://orcid.org/0000-0001-9066-3745
Arne OhlendorfInstitute for Ophthalmic Research, Eberhard Karls University Tuebingen, 72076, Tübingen, Germany.
Siegfried WahlInstitute for Ophthalmic Research, Eberhard Karls University Tuebingen, 72076, Tübingen, Germany.ORCID http://orcid.org/0000-0003-3437-6711

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myopic axial eye growth has mechanical implications on ocular structures, such as the retinal and foveal shape integrity or choroidal thickness. The current study investigated myopia-related changes of retinal radius of curvature, foveal width, depth, slope and choroidal thickness. Wide-field swept-source OCT line and volume scans were performed on 40 young adult participants in horizontal and vertical directions. OCT scans were corrected for their scan display distortions before automated extraction of retinal and foveal shape parameters. All findings were correlated to refractive error and axial length. The horizontal retinal radius of curvature and the directional ratio between horizontal and vertical retinal shape correlated significantly with axial length ([Formula: see text] and [Formula: see text]). Vertical retinal shape and foveal pit parameters neither showed any significant correlations with axial length nor refractive error (all [Formula: see text] 0.05). Choroidal thickness correlated significantly with refractive error in all analyzed regions ([Formula: see text]), but less with axial length ([Formula: see text] to - 0.37). Horizontal retinal shape and choroidal thickness, but not foveal pit morphology, were altered by myopic eye growth. Asymmetries in horizontal versus vertical retinal shape with increasing myopia were detected. These parameters could act as promising biomarkers for myopia and its associated complications.

Indexed as

AdultFemaleFovea CentralisHumansMaleMyopiaPilot ProjectsProspective StudiesRefractive ErrorsRetinaTomography, Optical CoherenceYoung Adult

Identifiers

PMID32616797
PMCPMC7331682

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.