Evidence map›Paper›PMID 32616751›Full record

ArticleScientific reports2020

Unveiling antimicrobial and anticancerous behavior of AuNPs and AgNPs moderated by rhizome extracts of Curcuma longa from diverse altitudes of Himalaya.

Mamta Sharma, Monika, Pankaj Thakur, Reena V Saini, Rajesh Kumar, Enza Torino

Open access · goldAbstract readComparative Study
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 52 citations in OpenAlex.

  1. Review
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  4. Protective Effects of Dietary Vitamin DPharmaceuticals (Basel, Switzerland) · 2024
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  7. Biocompatible CuInSACS omega · 2021
    Article
  8. Silver nanoparticles as a potential treatment against SARS-CoV-2: A review.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Mamta SharmaSchool of Biological and Environmental Sciences, Shoolini University, Solan, 173212, India. mamta131526@gmail.com.
MonikaSchool of Biological and Environmental Sciences, Shoolini University, Solan, 173212, India.
Pankaj ThakurSchool of Chemistry, Shoolini University, Solan, 173212, India.
Reena V SainiSchool of Biotechnology and Applied Sciences, Shoolini University, Solan, India.
Rajesh KumarSchool of Physics and Materials Sciences, Shoolini University, Solan, India. rajeshsharma@shooliniuniversity.com.
Enza TorinoCenter for Advanced Biomaterials for Healthcare, Italian Institute of Technology, 80125, Naples, Italy.
Shoolini University · INCenter for Advanced Biomaterials for Healthcare · ITHimalayan University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Conservative remedies have a gray history worldwide and these provide productive and pertinent tools to tackle ailments. Also, the high altitude areas of Indian Himalayas with their wealthy biodiversity anchorage around 2000 plant species. Ensuing study demonstrates the synthesis of Silver (Ag) and gold (Au) nanoparticles (NPs) and utilizes one of the medicaments Curcuma longa of Indian Himalayas collected from different altitudes. For the same, turmeric rhizome extracts have been prepared from the aforesaid medicament and its anticancer activity and antimicrobial potential have been evaluated. Formation of Ag and Au nanoparticles was realized via UV-Vis spectroscopy and transmission electron microscope (TEM) confirmed size of the NPs. Antibacterial activity has been checked against Bacillus subtilis and Escherichia coli. The anticancer prospective has been observed against A549 and PC3 cell lines of both Au and Ag NPs and the cytotoxicity on PC3 and A549 cell lines was assessed using MTT assay. Results revealed higher amount of biochemicals, antibacterial and anticancer activity in Ag and Au NPs synthesized from rhizome extract collected from highest altitude. For the first time impact of altitudinal variations on phytochemicals and nanoparticles has been reported which have significant effect on its antimicrobial and anticancerous activity.

Indexed as

Metal NanoparticlesAltitudeAnti-Bacterial AgentsAntineoplastic Agents, PhytogenicBacillus subtilisCell Line, TumorCurcumaDrug Evaluation, PreclinicalDrug Screening Assays, AntitumorEscherichia coliGoldHumansPlant ExtractsRhizomeSilverAnti-Bacterial AgentsAntineoplastic Agents, PhytogenicGoldPlant ExtractsSilverturmeric extract

Identifiers

PMID32616751
PMCPMC7331668
OpenAlexW3039509605

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.