ArticleScientific reports2020
Suppression of chorismate synthase, which is localized in chloroplasts and peroxisomes, results in abnormal flower development and anthocyanin reduction in petunia.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed, 24 citations in OpenAlex.
- 3-dehydroquinate synthase contributes to anthocyanin accumulation and flower pigmentation in petunia.Protoplasma · 2026Article
- Transketolase-mediated erythrose-4-phosphate provides an essential source for anthocyanin biosynthesis in petunia.Horticulture research · 2025Article
- Soil Properties Induced Changes in the Microbial Communities Associated With Potato Tubers Grown in Different Lowland Fields of Northern Thailand.MicrobiologyOpen · 2025Article
- Comparative Effects of Non-Composted and Composted Sewage Sludge from Wastewater Treatment Plants on the Physiological and Antioxidative Responses of Maize.Plants (Basel, Switzerland) · 2025Article
- Suppression of Chorismate Mutase 1 in Hybrid Poplar to Investigate Potential Redundancy in the Supply of Lignin Precursors.Plant direct · 2025Article
- Characterization of Thirty Germplasms of Millet Pepper (Metabolites · 2025Article
- Metabolomic and transcriptomic analyses unveil the accumulation of shikimic acid in the leaves ofFrontiers in plant science · 2025Article
- Functional Divergence of the Closely Related Genes PhARF5 and PhARF19a inInternational journal of molecular sciences · 2024Article
- Uncovering novel genes for drought stress in rice at germination stage using genome wide association study.Frontiers in plant science · 2024Article
- A long non-coding RNAPeerJ · 2023Article
- Shikimate Kinase Plays Important Roles in Anthocyanin Synthesis in Petunia.International journal of molecular sciences · 2022Article
- Revisiting the dual pathway hypothesis of Chorismate production in plants.Horticulture research · 2022Article
- Nitric Oxide (NO) Scaffolds the Peroxisomal Protein-Protein Interaction Network in Higher Plants.International journal of molecular sciences · 2021Review
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Authors and funding
6 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
In plants, the shikimate pathway generally occurs in plastids and leads to the biosynthesis of aromatic amino acids. Chorismate synthase (CS) catalyses the last step of the conversion of 5-enolpyruvylshikimate 3-phosphate (EPSP) to chorismate, but the role of CS in the metabolism of higher plants has not been reported. In this study, we found that PhCS, which is encoded by a single-copy gene in petunia (Petunia hybrida), contains N-terminal plastidic transit peptides and peroxisomal targeting signals. Green fluorescent protein (GFP) fusion protein assays revealed that PhCS was localized in chloroplasts and, unexpectedly, in peroxisomes. Petunia plants with reduced PhCS activity were generated through virus-induced gene silencing and further characterized. PhCS silencing resulted in reduced CS activity, severe growth retardation, abnormal flower and leaf development and reduced levels of folate and pigments, including chlorophylls, carotenoids and anthocyanins. A widely targeted metabolomics analysis showed that most primary and secondary metabolites were significantly changed in pTRV2-PhCS-treated corollas. Overall, the results revealed a clear connection between primary and specialized metabolism related to the shikimate pathway in petunia.
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