Evidence map›Paper›PMID 32616668›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2020

An Astrocytic Influence on Impaired Tonic Inhibition in Hippocampal CA1 Pyramidal Neurons in a Mouse Model of Rett Syndrome.

Qiping Dong, Jason Kim, Linh Nguyen, Qian Bu, Qiang Chang

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 27 citations in OpenAlex.

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  8. Paradoxical Hyperexcitability in Disorders of Neurodevelopment.Frontiers in molecular neuroscience · 2022
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Qiping DongWaisman Center, University of Wisconsin-Madison, Madison, Wisconsin 53705.ORCID 0000-0003-4668-9264
Jason KimWaisman Center, University of Wisconsin-Madison, Madison, Wisconsin 53705.ORCID 0000-0002-5551-5445
Linh NguyenWaisman Center, University of Wisconsin-Madison, Madison, Wisconsin 53705.
Qian BuWaisman Center, University of Wisconsin-Madison, Madison, Wisconsin 53705.ORCID 0000-0001-8629-7279
Qiang ChangWaisman Center, University of Wisconsin-Madison, Madison, Wisconsin 53705 qchang@waisman.wisc.edu.ORCID 0000-0002-7625-2170
University of Wisconsin–Madison · US

Funding

Waisman Intellectual and Developmental Disabilities Research Center Down Syndrome RegistryU54HD090256 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI MESSING, ALBEE · 2016 to 2020
$6.0M
In Vivo Function of Neuronal Activity-Induced MeCP2 phosphorylationR01HD064743 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI CHANG, QIANG · 2010 to 2021
$3.0M
Astrocyte dysfunction in Rett syndromeR56NS100024 · NINDS · UNIVERSITY OF WISCONSIN-MADISON · PI CHANG, QIANG · 2017 to 2017
$383k
NICHD NIH HHS R01 HD064743NICHD NIH HHS U54 HD090256NINDS NIH HHS R56 NS100024
6 · The paper itself

Abstract

Rett syndrome (RTT) is a severe neurodevelopmental disease caused by mutations in the methyl-CpG binding protein 2 (

Indexed as

Neural InhibitionAnimalsAstrocytesCA1 Region, HippocampalGABA Plasma Membrane Transport Proteinsgamma-Aminobutyric AcidMaleMethyl-CpG-Binding Protein 2MicePyramidal CellsReceptors, GABARett SyndromeGABA Plasma Membrane Transport Proteinsgamma-Aminobutyric AcidMecp2 protein, mouseMethyl-CpG-Binding Protein 2Receptors, GABAastrocyteGABA transporterMeCP2mouse modelRett syndrometonic inhibition

Identifiers

PMID32616668
PMCPMC7406277
OpenAlexW3040365400

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.