Evidence map›Paper›PMID 32616573›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2020

Revealing 29 sets of independently modulated genes in

Saugat Poudel, Hannah Tsunemoto, Yara Seif, Anand V Sastry, Richard Szubin, Sibei Xu, Henrique Machado, Connor A Olson, Amitesh Anand, Joe Pogliano and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed
1.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 97 citations in OpenAlex.

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  8. Characterizing theJournal of bacteriology · 2025
    Article
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  11. Integrated genomic and proteomic analysis of the mouse-adaptedCurrent research in microbial sciences · 2025
    Article
  12. Current models in bacterial hemicellulase-encoding gene regulation.Applied microbiology and biotechnology · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Saugat PoudelDepartment of Bioengineering, University of California San Diego, La Jolla, CA 92093.ORCID 0000-0002-3732-2463
Hannah TsunemotoDepartment of Biology, University of California San Diego, La Jolla, CA 92093.
Yara SeifDepartment of Bioengineering, University of California San Diego, La Jolla, CA 92093.ORCID 0000-0001-8813-5679
Anand V SastryDepartment of Bioengineering, University of California San Diego, La Jolla, CA 92093.
Richard SzubinDepartment of Bioengineering, University of California San Diego, La Jolla, CA 92093.
Sibei XuDepartment of Bioengineering, University of California San Diego, La Jolla, CA 92093.
Henrique MachadoDepartment of Bioengineering, University of California San Diego, La Jolla, CA 92093.
Connor A OlsonDepartment of Bioengineering, University of California San Diego, La Jolla, CA 92093.
Amitesh AnandDepartment of Bioengineering, University of California San Diego, La Jolla, CA 92093.ORCID 0000-0002-3720-4301
Joe PoglianoDepartment of Biology, University of California San Diego, La Jolla, CA 92093.
Victor NizetCollaborative to Halt Antibiotic-Resistant Microbes, Department of Pediatrics, University of California San Diego, La Jolla, CA 92093.ORCID 0000-0003-3847-0422
Bernhard O PalssonDepartment of Bioengineering, University of California San Diego, La Jolla, CA 92093; palsson@ucsd.edu.ORCID 0000-0003-2357-6785
University of California San Diego · US

Funding

Systems Biology Approach to Redefine Susceptibility Testing and Treatment of MDR Pathogens in the Context of Host ImmunityU01AI124316 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI PALSSON, BERNHARD O · 2016 to 2020
$10.2M
Safety and Dose Optimization of High-Dose Anakinra in Kawasaki DiseaseP50HD090259 · NICHD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CAPPARELLI, EDMUND VINCENT, NIZET, VICTOR · 2019 to 2020
$1.4M
NIAID NIH HHS U01 AI124316NICHD NIH HHS P50 HD090259
6 · The paper itself

Abstract

The ability of

Indexed as

Gene Expression Regulation, BacterialTranscriptomeBacterial ProteinsDNA-Binding ProteinsGene Regulatory NetworksMetabolic Networks and PathwaysRepressor ProteinsSequence Analysis, RNASigma FactorStaphylococcal InfectionsStaphylococcus aureusVirulenceVirulence FactorsBacterial ProteinsCodY protein, Staphylococcus aureusDNA-Binding ProteinsRepressor ProteinsSigma Factorsigma factor KatF protein, BacteriaVirulence FactorsmetabolismStaphylococcus aureustranscriptional regulatory networkvirulence

Identifiers

PMID32616573
PMCPMC7382225
OpenAlexW3039562686

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.