Evidence map›Paper›PMID 32616253›Full record

ArticlePoultry science2020

Cellular markers of mule duck livers after force-feeding.

Bara Lo, Nathalie Marty-Gasset, Hélène Manse, Carole Bannelier, Céline Bravo, Renaud Domitile, Hervé Rémignon

Open access · goldAbstract read
In one paragraph

Article in Poultry science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Bara LoGenPhySE, Université de Toulouse, INRAE, ENVT, 31326 Castanet Tolosan, France.
Nathalie Marty-GassetGenPhySE, Université de Toulouse, INRAE, ENVT, 31326 Castanet Tolosan, France.
Hélène ManseGenPhySE, Université de Toulouse, INRAE, ENVT, 31326 Castanet Tolosan, France.
Carole BannelierGenPhySE, Université de Toulouse, INRAE, ENVT, 31326 Castanet Tolosan, France.
Céline BravoGenPhySE, Université de Toulouse, INRAE, ENVT, 31326 Castanet Tolosan, France.
Renaud DomitileIDENA, Sautron 44880, France.
Hervé RémignonGenPhySE, Université de Toulouse, INRAE, ENVT, 31326 Castanet Tolosan, France. Electronic address: remignon@ensat.fr.
Génétique Physiologie et Systèmes d'Elevage · FRInstitut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement · FRUniversité Fédérale de Toulouse Midi-Pyrénées · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The "Foie gras" or fatty liver is the result of hepatic steatosis from nutritional origin and induced by the force-feeding of palmipeds. Despite identical rearing and force-feeding conditions of ducks from the same breed, different liver weights, within a range of 500 to more than 700 g, are generally observed at the time of evisceration. To better understand the determinism of this large variability in fatty liver weights, the activity of various metabolic pathways has been explored in 4 groups of steatotic livers differing by their weights. Different analyses were performed using biochemical assays on metabolites as well as ELISA tests or enzyme activity assays. The result showed that an increase in the final liver weight is always associated with a hypoxic response and even a severe hypoxia observed in livers with the highest weights (more than 650 g). This is also combined with a rise in the cellular oxidative stress level. In addition, for the heaviest livers (more than 700 g), signs of cell death by apoptosis were also observed, while others programmed cell death pathways, such as ferroptosis or necroptosis, seemed to be nonactive.

Indexed as

AnimalsBiomarkersDucksEnteral NutritionFatty LiverLiverBiomarkerscell deathFoie grashypoxiamule duckoxidative stress

Identifiers

PMID32616253
PMCPMC7597809
OpenAlexW3018783896

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.