Evidence map›Paper›PMID 32616019›Full record

ArticleBMC psychiatry2020

Adherence among HIV-positive injection drug users undergoing methadone treatment in Taiwan.

En Chao, Chia-Chun Hung, Ching-Po Lin, Yi-Chien Jacob Ku, Qurat Ul Ain, David S Metzger, Tony Szu-Hsien Lee

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in BMC psychiatry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

En Chao *Department of Health Promotion and Health Education, National Taiwan Normal University, Taipei, Taiwan.
Chia-Chun Hung *Institute of Brain Science, National Yang Ming University, Taipei, Taiwan.
Ching-Po LinInstitute of Brain Science, National Yang Ming University, Taipei, Taiwan.
Yi-Chien Jacob KuDepartment of Health Promotion and Health Education, National Taiwan Normal University, Taipei, Taiwan.
Qurat Ul AinDepartment of Health Promotion and Health Education, National Taiwan Normal University, Taipei, Taiwan.
David S MetzgerDepartment of Psychiatry, University of Pennsylvania, Philadelphia, USA.
Tony Szu-Hsien LeeDepartment of Health Promotion and Health Education, National Taiwan Normal University, Taipei, Taiwan. tonylee@ntnu.edu.tw.ORCID http://orcid.org/0000-0003-2574-3372
National Taiwan Normal University · TWNational Yang Ming Chiao Tung University · TWUniversity of Pennsylvania · US

Funding

Virus & Reservoirs CoreP30AI045008 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI Ronald G Collman · 1999 to 2026
$78.6M
University of Pennsylvania HIV Clinical Trials UnitUM1AI069534 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI Ian Frank, PABLO TEBAS · 2012 to 2026
$33.0M
Penn Mental Health AIDS Research CenterP30MH097488 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI Karine Dube, Kelly L Jordan-Sciutto · 2013 to 2026
$23.5M
Ministry of Science and Technology, Taiwan 103-2410-H-003-022NIAID NIH HHS P30 AI045008NIAID NIH HHS UM1 AI069534NIMH NIH HHS P30 MH097488
6 · The paper itself

Abstract

aimsThe study aims were to investigate adherence to methadone maintenance treatment (MMT) and to identify associated clinical factors in patients who inject drugs diagnosed with human immunodeficiency virus (HIV) infection in Taiwan.

methodsData were from the National Health Surveillance System on HIV and the National Drug Treatment System on MMT. HIV-positive people who inject drugs (HIVPWID) were defined as the study population. Information obtained included age, sex, education, marital status, employment, methadone dose, and date of diagnosis of HIV infection. Adherence was defined as taking methadone for the past 90, 180 and 365 days, then categorized as high (> 90%), moderate (51 to 90%), or low (<=50%) adherent respectively.

resultsOf 1641 HIVPWID registered in the datasets from 2007 to 2012, 961 (58.56%) had received MMT. For HIVPWID evaluated at 90 days (n = 951), 271 (28.5%), 382 (40.2%), and 298 (31.3%) were classified as high, moderate, and low adherent respectively. For HIVPWID evaluated at 180 days (n = 936), 190 (20.3%), 349 (37.3%), and 397 (42.4%) were classified as high, moderate, and low adherent respectively. For HIVPWID evaluated at 365 days (n = 919), 133 (14.5%), 271 (29.5%), and 515 (56.0%) were classified as high, moderate, and low adherent respectively. After controlling for sociodemographics, results showed that methadone dose, location of MMT clinic, and date of HIV diagnosis were significantly associated with MMT adherence.

conclusionsStudy findings underscore the importance to MMT adherence of methadone dosage, early diagnosis of patient's HIV infection, and area of patient residence.

Indexed as

Drug UsersHIV InfectionsHumansMethadoneOpiate Substitution TreatmentTaiwanMethadoneAdherenceDaily doseHIVInjection drug useMethadone maintenance treatmentRetention

Identifiers

PMID32616019
PMCPMC7331024
OpenAlexW3040537449

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.