Evidence map›Paper›PMID 32616011›Full record

ArticleBMC research notes2020

Establishment of reference range of CD4 T-lymphocyte in healthy Nepalese adults.

Shravan Kumar Mishra, Lilee Shrestha, Roshan Pandit, Sundar Khadka, Bimal Shrestha, Subhash Dhital, Saroj Sharma, Mukunda Sharma, Raj Kumar Mahato, Geeta Shakya and 1 more

Abstract read
In one paragraph

Article in BMC research notes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Shravan Kumar MishraNational Public Health Laboratory, Department of Health Services, Ministry of Health and Population, Kathmandu, Nepal.
Lilee ShresthaNational Public Health Laboratory, Department of Health Services, Ministry of Health and Population, Kathmandu, Nepal.
Roshan PanditNational Public Health Laboratory, Department of Health Services, Ministry of Health and Population, Kathmandu, Nepal. roshanpandit2050@gmail.com.ORCID http://orcid.org/0000-0003-2946-1233
Sundar KhadkaNational Public Health Laboratory, Department of Health Services, Ministry of Health and Population, Kathmandu, Nepal.
Bimal ShresthaNational Public Health Laboratory, Department of Health Services, Ministry of Health and Population, Kathmandu, Nepal.
Subhash DhitalNational Public Health Laboratory, Department of Health Services, Ministry of Health and Population, Kathmandu, Nepal.
Saroj SharmaKanti Children Hospital, Maharajgunj, Kathmandu, Nepal.
Mukunda SharmaNational Public Health Laboratory, Department of Health Services, Ministry of Health and Population, Kathmandu, Nepal.
Raj Kumar MahatoNational Public Health Laboratory, Department of Health Services, Ministry of Health and Population, Kathmandu, Nepal.
Geeta ShakyaNational Public Health Laboratory, Department of Health Services, Ministry of Health and Population, Kathmandu, Nepal.
Krishna Das ManandharCentral Department of Biotechnology, Institute of Science and Technology, Tribhuvan University, Kathmandu, Nepal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveCD4 T lymphocytes are the most widely used cellular markers to assess the course of HIV infection, clinical staging and, monitoring the effect of antiretroviral therapy. The regional reference range for Eastern, Central and Western development region of Nepal had already been established whereas the same was still lacking in Mid-western and Far-western development region. The objective of this study was to establish reference range of CD4 T lymphocyte in the remaining two development regions and finally the national reference range using data from previous study.

resultsThe average values (mean ± SD) of CD4 and CD3 T cell in present study was (819 ± 294) cells/μl and (1546 ± 532) cells/μl, respectively. The absolute CD4 T cell (914 ± 303) and CD3 T cell (1671 ± 560) count in female were significantly higher than those from male, CD4 (757 ± 270) and CD3 (1465 ± 499) (p value-0.000). National reference value of CD4 was determined to be (798 ± 335) cells/μl for healthy Nepalese adults.

Indexed as

AdolescentAdultCD4 Lymphocyte CountCross-Sectional StudiesFemaleHumansMaleMiddle AgedNepalReference ValuesYoung AdultCD3CD4NepalReference rangeT-lymphocyte

Identifiers

PMID32616011
PMCPMC7330941

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