Evidence map›Paper›PMID 32616010›Full record

ArticleBMC research notes2020

Detecting bracoviral orthologs distribution in five tsetse fly species and the housefly genomes.

Kelvin M Kimenyi, Muna F Abry, Winnie Okeyo, Enock Matovu, Daniel Masiga, Benard W Kulohoma

Abstract read
In one paragraph

Article in BMC research notes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kelvin M KimenyiCentre for Biotechnology and Bioinformatics, University of Nairobi, P.O. Box 30197, Nairobi, 00100, Kenya.
Muna F AbryCentre for Biotechnology and Bioinformatics, University of Nairobi, P.O. Box 30197, Nairobi, 00100, Kenya.
Winnie OkeyoInternational Centre of Insect Physiology and Ecology, P.O. Box 30772, Nairobi, 00100, Kenya.
Enock MatovuMakerere University, P.O. Box 7062, Kampala, Uganda.
Daniel MasigaInternational Centre of Insect Physiology and Ecology, P.O. Box 30772, Nairobi, 00100, Kenya.
Benard W KulohomaCentre for Biotechnology and Bioinformatics, University of Nairobi, P.O. Box 30197, Nairobi, 00100, Kenya. bkulohoma@uonbi.ac.ke.ORCID http://orcid.org/0000-0001-6825-1832

Funding

Wellcome TrustWellcome Trust 087540
6 · The paper itself

Abstract

objectiveMutualism between endogenous viruses and eukaryotes is still poorly understood. Several endogenous double-stranded polydnaviruses, bracoviruses, homologous to those present in parasitic braconid wasp genomes were detected in the tsetse fly (Glossina morsitans morsitans). This is peculiar since tsetse flies do not share a reproductive lifestyle similar to wasps, but deliver fully developed larvae that pupate within minutes of exiting their mothers. The objective of this study is to investigate genomic distribution of bracoviral sequences in five tsetse fly species and the housefly, and examine its value as a potential vector control strategy target point. We use comparative genomics to determine the presence, distribution across Glossina species genomes, and evolutionary relationships of bracoviruses of five tsetse fly species and the housefly.

resultsWe report on homologous bracoviruses in multiple Dipteran genomes. Phylogenetic reconstruction using within-species concatenated bracoviral orthologs shows great congruence with previously reconstructed insect species phylogenies. Our findings suggest that bracoviruses present in Diptera originate from a single integration event of the viral genome that occurred in an ancestor insect before the evolutionary radiation of different insect orders.

Indexed as

AnimalsGenome, InsectHousefliesPhylogenyPolydnaviridaeTsetse FliesBracovirusesEndogenous virusesEukaryotesHouseflyTsetse fly

Identifiers

PMID32616010
PMCPMC7331153

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.