Evidence map›Paper›PMID 32615862›Full record

ReviewEmerging microbes & infections2020

Profiles of COVID-19 clinical trials in the Chinese Clinical Trial Registry.

Peng Xu, Xiangyu Xing, Keying Yu, Zhiguo Lv, Huijing Cui, Yuhang Shi, Tianying Chang, Dongmei Zhang, Yibin Zhang, Kai Wang and 8 more

Abstract readReview
In one paragraph

Review in Emerging microbes & infections, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Peng XuNeurology Department, The Affiliated Hospital to Changchun University of Chinese Medicine, Changchun, People's Republic of China.
Xiangyu XingDepartment of Hepatology, The First Hospital of Jilin University, Changchun, People's Republic of China.ORCID https://orcid.org/0000-0001-5122-6446
Keying YuCardiovascular Medicine Department, The Affiliated Hospital to Changchun University of Chinese Medicine, Changchun, People's Republic of China.
Zhiguo LvNeurology Department, The Affiliated Hospital to Changchun University of Chinese Medicine, Changchun, People's Republic of China.
Huijing CuiTraditional Chinese Medicine Department, Nanguan District Traditional Chinese Medicine Hospital, Changchun, People's Republic of China.
Yuhang ShiDepartment of Gerontology, The Changchun Hospital of TCM, Changchun, People's Republic of China.
Tianying ChangGCP Department, The Affiliated Hospital to Changchun University of Chinese Medicine, Changchun, People's Republic of China.
Dongmei ZhangScientific Research Office, The Affiliated Hospital to Changchun University of Chinese Medicine, Changchun, People's Republic of China.
Yibin ZhangCollege of Traditional Chinese Medicine, Changchun University of Chinese Medicine, Changchun, People's Republic of China.
Kai WangCollege of Traditional Chinese Medicine, Changchun University of Chinese Medicine, Changchun, People's Republic of China.
Jing LuResearch Center of Traditional Chinese Medicine, The Affiliated Hospital to Changchun University of Chinese Medicine, Changchun, People's Republic of China.
Qingxia HuangResearch Center of Traditional Chinese Medicine, The Affiliated Hospital to Changchun University of Chinese Medicine, Changchun, People's Republic of China.
Xiangyan LiJilin Ginseng Academy, Jilin Provincial Key Laboratory of BioMacromolecules of Chinese Medicine, Changchun University of Chinese Medicine, Changchun, People's Republic of China.
Yingzi CuiGCP Department, The Affiliated Hospital to Changchun University of Chinese Medicine, Changchun, People's Republic of China.
Li ShiRespiratory Medicine Department, The Affiliated Hospital to Changchun University of Chinese Medicine, Changchun, People's Republic of China.
Tan WangRespiratory Medicine Department, The Affiliated Hospital to Changchun University of Chinese Medicine, Changchun, People's Republic of China.
Junqi NiuDepartment of Hepatology, The First Hospital of Jilin University, Changchun, People's Republic of China.
Jian WangNeurology Department, The Affiliated Hospital to Changchun University of Chinese Medicine, Changchun, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The COVID-19 pandemic has caused a global public health crisis. There is a pressing need for evidence-based interventions to address the devastating clinical and public health effects of the COVID-19 pandemic. The Chinese scientists supported by private and government resources have adopted extensive efforts to identify effective drugs against the virus. To date, a large number of clinical trials addressing various aspects of COVID19 have been registered in the Chinese Clinical Trial Registry (ChiCTR), including more than 200 interventional studies. Under such an urgent circumstance, the scope and quality of these clinical studies vary significantly. Hence, this review aims to make a comprehensive analysis on the profiles of COVID-19 clinical trials registered in the ChiCTR, including a wide range of characteristics. Our findings will provide a useful summary on these clinical studies since most of these studies will encounter major challenges from the design to completion. It will be a long road for the outcomes of these studies to be published and international collaboration will help the ultimate goals of developing new vaccines and anti-viral drugs.

Indexed as

BetacoronavirusRegistriesAntiviral AgentsChinaClinical Trials as TopicCoronavirus InfectionsCOVID-19HumansMedicine, Chinese TraditionalPandemicsPneumonia, ViralResearch DesignSARS-CoV-2Antiviral Agentsanti-viral drugclinical trialsCOVID-19Traditional Chinese Medicinevaccine

Identifiers

PMID32615862
PMCPMC7473047

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.