Evidence map›Paper›PMID 32615714›Full record

ArticleEndocrinology and metabolism (Seoul, Korea)2020

Effects of a Portfolio-Mediterranean Diet and a Mediterranean Diet with or without a Sterol-Enriched Yogurt in Individuals with Hypercholesterolemia.

Yvelise Ferro, Elisa Mazza, Mariantonietta Salvati, Emma Santariga, Salvatore Giampà, Rocco Spagnuolo, Patrizia Doldo, Roberta Pujia, Adriana Coppola, Carmine Gazzaruso and 2 more

Open access · diamondAbstract readComparative Study
In one paragraph

Article in Endocrinology and metabolism (Seoul, Korea), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Yvelise FerroDepartment of Health Science, University Magna Grecia, Catanzaro, Italy.
Elisa MazzaNutrition Unit, Department of Medical and Surgical Science, University Magna Grecia, Catanzaro, Italy.
Mariantonietta SalvatiNutrition Unit, Department of Medical and Surgical Science, University Magna Grecia, Catanzaro, Italy.
Emma SantarigaNutrition Unit, Department of Medical and Surgical Science, University Magna Grecia, Catanzaro, Italy.
Salvatore GiampàNutrition Unit, Department of Medical and Surgical Science, University Magna Grecia, Catanzaro, Italy.
Rocco SpagnuoloDepartment of Clinical and Experimental Medicine, University Magna Grecia, Catanzaro, Italy.
Patrizia DoldoDepartment of Clinical and Experimental Medicine, University Magna Grecia, Catanzaro, Italy.
Roberta PujiaDepartment of Health Science, University Magna Grecia, Catanzaro, Italy.
Adriana CoppolaDepartment of Internal and Emergency Medicine and Centre for Applied Clinical Research, Beato Matteo Institute, Vigevano, Italy.
Carmine GazzarusoDepartment of Internal and Emergency Medicine and Centre for Applied Clinical Research, Beato Matteo Institute, Vigevano, Italy.
Arturo PujiaNutrition Unit, Department of Medical and Surgical Science, University Magna Grecia, Catanzaro, Italy.
Tiziana MontalciniDepartment of Clinical and Experimental Medicine, University Magna Grecia, Catanzaro, Italy.
Magna Graecia University · ITComelz (Italy) · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA growing number of functional foods have been proposed to reduce cholesterol levels and the Portfolio Diet, which includes a combination of plant sterols, fibres, nuts, and soy protein, reduces low density lipoprotein cholesterol (LDL-C) from 20% to 30% in individuals with hyperlipidaemia. In this pilot study, the aim was to investigate whether a Mediterranean Diet incorporating a new and simple combination of cholesterol-lowering foods, excluding soy and nuts (namely the Portfolio-Mediterranean Diet), would reduce LDL-C levels, in the short-term, better than a Mediterranean Diet plus a sterol-enriched yogurt or a Mediterranean Diet alone.

methodsWe retrospectively evaluated 24 individuals on a Portfolio-Mediterranean Diet and 48 matched individuals on a Mediterranean Diet with or without a sterol-enriched yogurt (24 each groups) as controls.

resultsAt follow-up (after 48±12 days), we observed an LDL reduction of 21±4, 23±4, and 44±4 mg/dL in the Mediterranean Diet alone, Mediterranean Diet plus yogurt and Portfolio-Mediterranean Diet respectively (P<0.001).

conclusionA Portfolio-Mediterranean Diet, incorporating a new combination of functional foods such as oats or barley, plant sterols, chitosan, and green tea but not soy and nuts, may reduce LDL of 25% in the short term in individuals with hypercholesterolemia.

Indexed as

Case-Control StudiesDiet, MediterraneanFemaleFollow-Up StudiesHumansHypercholesterolemiaMaleMiddle AgedPrognosisRetrospective StudiesSterolsYogurtSterolsAnticholesteremic agentsCholesterol, LDLDiet, MediterraneanYogurt

Identifiers

PMID32615714
PMCPMC7386117
OpenAlexW3039075677

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.