ArticleAnnals of pediatric endocrinology & metabolism2020
Serum uric acid in Korean children and adolescents: reference percentiles and association with metabolic syndrome.
Article in Annals of pediatric endocrinology & metabolism, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
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Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Recent advances in research on the association between paediatric hyperuricaemia and bone health.Frontiers in endocrinology · 2026Pooled it
- Can biomarkers be used to improve diagnosis and prediction of metabolic syndrome in childhood cancer survivors? A systematic review.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2021Pooled it
- Serum uric acid levels among children and adolescents in China: percentile reference values and national prevalence estimates of hyperuricemia.BMC medicine · 2026Article
- Pediatric hyperuricemia: genetic basis, metabolic mechanisms, and clinical implications.Frontiers in endocrinology · 2026Review
- Association between serum uric acid and kidney disease with pediatric focus.Childhood kidney diseases · 2024Review
- Trends in serum uric acid levels among Korean children and adolescents between 2016 and 2020: a nationwide study.European journal of pediatrics · 2023Article
- Skeptical Look at the Clinical Implication of Metabolic Syndrome in Childhood Obesity.Children (Basel, Switzerland) · 2023Review
- Association of serum uric acid Levels with metabolic syndromes in Korean adolescents.Frontiers in endocrinology · 2023Article
- Association between the uric acid to high density lipoprotein cholesterol ratio and alanine transaminase in Chinese short stature children and adolescents: A cross-sectional study.Frontiers in nutrition · 2023Article
- Comparison between School-Age Children with and without Obesity in Nutritional and Inflammation Biomarkers.Journal of clinical medicine · 2022Article
- Article
- Relationship between bisphenol A, bisphenol S, and bisphenol F and serum uric acid concentrations among school-aged children.PloS one · 2022Article
- Association between uric acid and height during growth hormone therapy in children with idiopathic short stature.Frontiers in endocrinology · 2022Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo establish age/sex-specific reference intervals for serum uric acid and to examine the associations between serum uric acid level and metabolic syndrome (MetS) and its components in Korean children and adolescents.
methodsWe analyzed data for 1,349 subjects aged 10 to 19 years from the Korea National Health and Nutrition Examination Survey 2016-2017.
resultsThe mean uric acid levels were 5.9±1.3 mg/dL (interquartile range, 5.0-6.8 mg/dL) in males and 4.6±0.9 mg/dL (interquartile range, 3.9-5.2 mg/dL) in females. The mean uric acid level increased significantly from 10-13 years of age in males, but not in females. The overall prevalence of MetS was 5.9% (7.3% in males and 4.3% in females; P=0.022). The prevalences of MetS in the lowest, second, third, and highest quartiles of uric acid level were 4.4%, 3.3%, 6.1%, and 15.2%, respectively, in males (P for trend <0.001) and 1.9%, 0.0%, 4.1%, and 10.9%, respectively, in females (P for trend <0.001). Compared with the lowest quartile of uric acid level, the odds ratio (with 95% confidence interval) for MetS in the highest quartile was 2.897 (1.140-7.361) in males and 5.173 (1.459-18.342) in females. Subjects in the highest quartile exhibited increased risk for abdominal obesity and low high-density lipoprotein cholesterol in both sexes.
conclusionSerum uric acid level is positively associated with MetS and its components abdominal obesity and low high-density lipoprotein cholesterol.
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