Evidence map›Paper›PMID 32614967›Full record

ArticleSleep2021

Suicidal ideation is associated with nighttime wakefulness in a community sample.

Andrew S Tubbs, Fabian-Xosé Fernandez, Michael L Perlis, Lauren Hale, Charles C Branas, Marna Barrett, Subhajit Chakravorty, Waliuddin Khader, Michael A Grandner

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in Sleep, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04986007 (Addressing Nocturnal Sleep/Wake Effects on Risk of Suicide in Older Adults), which is not on this map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04986007 naterminatednot on this map

Addressing Nocturnal Sleep/Wake Effects on Risk of Suicide in Older Adults (ANSWERS-OA): A Pilot, Open-Label, Randomized Controlled Trial of Digital Cognitive Behavioral Therapy for Insomnia

TypeinterventionalSponsorMICHAEL A GRANDNERRan2021 to 2025Enrolled23ConditionsSleep Initiation and Maintenance Disorders, Suicidal IdeationArmsDigital Cognitive Behavioral Therapy for Insomnia
3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 34 citations in OpenAlex.

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  9. [Insomniac symptoms and suicidality-link and management].Neuropsychiatrie : Klinik, Diagnostik, Therapie und Rehabilitation : Organ der Gesellschaft Osterreichischer Nervenarzte und Psychiater · 2024
    Review
  10. Article
  11. Animal models of human insomnia.Journal of sleep research · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Andrew S TubbsSleep and Health Research Program, Department of Psychiatry, University of Arizona, Tucson, AZ.
Fabian-Xosé FernandezDepartment of Psychology, BIO5 and McKnight Brain Research Institutes, University of Arizona, Tucson, AZ.
Michael L PerlisBehavioral Sleep Medicine Program, Department of Psychiatry, University of Pennsylvania, Philadelphia, PA.
Lauren HaleProgram in Public Health, Department of Family, Population, and Preventative Medicine, Renaissance School of Medicine, Stony Brook University, Stony Brook, NY.
Charles C BranasDepartment of Epidemiology, Columbia University, New York, NY.
Marna BarrettMood and Anxiety Disorders Treatment Research Program, Department of Psychiatry, University of Pennsylvania, Philadelphia, PA.
Subhajit ChakravortyBehavioral Sleep Medicine Program, Department of Psychiatry, University of Pennsylvania, Philadelphia, PA.
Waliuddin KhaderSleep and Health Research Program, Department of Psychiatry, University of Arizona, Tucson, AZ.
Michael A GrandnerSleep and Health Research Program, Department of Psychiatry, University of Arizona, Tucson, AZ.
University of Arizona · USUniversity of Pennsylvania · USColumbia University · USStony Brook School · US

Funding

Using Sleep Health to Optimize Smoking Cessation Treatment Response in HIV-Positive AdultsR01DA051321 · NIDA · UNIVERSITY OF ARIZONA · PI FANTRY, LORI E, GRANDNER, MICHAEL A · 2020 to 2024
$4.1M
Sleep and Cardiometabolic Health Disparities at the US/Mexico Border: The Nogales Cardiometabolic Health and Sleep (NoCHeS) StudyR01MD011600 · NIMHD · UNIVERSITY OF ARIZONA · PI GRANDNER, MICHAEL A · 2018 to 2022
$4.1M
Sleep and Health in the Social EnvironmentR21ES022931 · NIEHS · UNIVERSITY OF PENNSYLVANIA · PI GRANDNER, MICHAEL A · 2012 to 2013
$436k
NIDA NIH HHS R01 DA051321NIEHS NIH HHS R21 ES022931NIMHD NIH HHS R01 MD011600
6 · The paper itself

Abstract

STUDY

objectivesNocturnal wakefulness is a risk factor for suicide and suicidal ideation in clinical populations. However, these results have not been demonstrated in general community samples or compared to sleep duration or sleep quality. The present study explored how the timing of wakefulness was associated with suicidal ideation for weekdays and weekends.

methodsData were collected from 888 adults aged 22-60 as part of the Sleep and Healthy Activity, Diet, Environment, and Socialization study. Suicidal ideation was measured by the Patient Health Questionnaire-9, while timing of wakefulness was estimated from the Sleep Timing Questionnaire. Binomial logistic regressions estimated the association between nocturnal (11 pm-5 am) and morning (5 am-11 am) wakefulness and suicidal ideation.

resultsNocturnal wakefulness was positively associated with suicidal ideation on weekdays (OR: 1.44 [1.28-1.64] per hour awake between 11:00 pm and 05:00 am, p < 0.0001) and weekends (OR: 1.22 [1.08-1.39], p = 0.0018). Morning wakefulness was negatively associated with suicidal ideation on weekdays (OR: 0.82 [0.72-0.92] per hour awake between 05:00 am and 11:00 am, p = 0.0008) and weekends (OR: 0.84 [0.75-0.94], p = 0.0035). These associations remained significant when adjusting for sociodemographic factors. Additionally, nocturnal wakefulness on weekdays was associated with suicidal ideation when accounting for insomnia, sleep duration, sleep quality, and chronotype (OR 1.25 [1.09-1.44] per hour awake, p = 0.002).

conclusionWakefulness at night was consistently associated with suicidal ideation. Additionally, morning wakefulness was negatively associated with suicidal ideation in some models. Although these findings are drawn from a non-clinical sample, larger longitudinal studies in the general population are needed to confirm these results.

Indexed as

Sleep Initiation and Maintenance DisordersSuicideAdultHumansMiddle AgedRisk FactorsSleepSuicidal IdeationWakefulnessYoung Adultchronotypenocturnal wakefulnesssuicidal ideationsuicide

Identifiers

PMID32614967
PMCPMC8240658
OpenAlexW3039957348

What OpenQuestion holds

Textmetadata
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.