Evidence map›Paper›PMID 32614653›Full record

ArticleHuman vaccines & immunotherapeutics2021

The role of hepatitis B vaccine challenge dose in patients with underlying health conditions.

L Sticchi, I G Iavarone, P Durando, A Di Biagio, I Schiavetti, F Murgia, G Icardi

Open access · bronzeAbstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Human vaccines & immunotherapeutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

L SticchiDepartment of Health Sciences (Dissal), University of Genoa , Genoa, Italy.ORCID 0000-0002-7819-7400
I G IavaroneDepartment of Health Sciences (Dissal), University of Genoa , Genoa, Italy.ORCID 0000-0002-0096-7938
P DurandoDepartment of Health Sciences (Dissal), University of Genoa , Genoa, Italy.ORCID 0000-0001-5047-5176
A Di BiagioDepartment of Health Sciences (Dissal), University of Genoa , Genoa, Italy.
I SchiavettiDepartment of Health Sciences (Dissal), University of Genoa , Genoa, Italy.
F MurgiaHealthcare Profession Direction Operational Unit, IRCCS Policlinico San Martino Hospital , Genoa, Italy.
G IcardiDepartment of Health Sciences (Dissal), University of Genoa , Genoa, Italy.ORCID 0000-0002-8463-8487
Ospedale Policlinico San Martino · ITUniversity of Genoa · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We have evaluated the immunological response to Hepatitis B virus (HBV) booster vaccine dose in 129 adults with underlying diseases in comparison with 694 subjects at occupational risk of infection, who have previously completed the primary series and resulted with anti-HBs <10 mIU/mL. After booster dose, 60.5% of the patients with underlying diseases and 14.8% of the subjects at occupational risk resulted seronegative. By comparing two groups, rate of subjects with anamnestic response was higher in at occupational risk group respect to that at risk for medical conditions (OR: 5.99 [95%IC, 3.81-9.41],

Indexed as

Hepatitis BHepatitis B VaccinesAdultFemaleHepatitis B AntibodiesHepatitis B Surface AntigensHepatitis B virusHumansImmunization, SecondaryImmunologic MemoryMaleVaccinationHepatitis B AntibodiesHepatitis B Surface AntigensHepatitis B VaccinesHBVhealth care workersimmunocompromisedItalyvaccination

Identifiers

PMID32614653
PMCPMC7899643
OpenAlexW3039624528

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.