Evidence map›Paper›PMID 32613945›Full record

ArticleeLife2020

Cortical ChAT

Adam J Granger, Wengang Wang, Keiramarie Robertson, Mahmoud El-Rifai, Andrea F Zanello, Karina Bistrong, Arpiar Saunders, Brian W Chow, Vicente Nuñez, Miguel Turrero García and 3 more

Open access · goldAbstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed
6.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

64 citing papers in PubMed, 168 citations in OpenAlex.

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  8. Co-release of GABA and ACh from Medial Olivocochlear Neurons as a Fine Regulatory Mechanism of Cochlear Efferent Inhibition.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
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  17. GABA Receptors and KNeurochemical research · 2024
    Article
  18. Article
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4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Adam J GrangerHoward Hughes Medical Institute, Department of Neurobiology, Harvard Medical School, Boston, United States.ORCID 0000-0002-3953-6764
Wengang WangHoward Hughes Medical Institute, Department of Neurobiology, Harvard Medical School, Boston, United States.
Keiramarie RobertsonHoward Hughes Medical Institute, Department of Neurobiology, Harvard Medical School, Boston, United States.
Mahmoud El-RifaiNeurobiology Imaging Facility, Department of Neurobiology, Harvard Medical School, Boston, United States.
Andrea F ZanelloHoward Hughes Medical Institute, Department of Neurobiology, Harvard Medical School, Boston, United States.
Karina BistrongHoward Hughes Medical Institute, Department of Neurobiology, Harvard Medical School, Boston, United States.
Arpiar SaundersDepartment of Genetics, Harvard Medical School, Boston, United States.
Brian W ChowDepartment of Neurobiology, Harvard Medical School, Boston, United States.
Vicente NuñezDepartment of Neurobiology, Harvard Medical School, Boston, United States.
Miguel Turrero GarcíaDepartment of Neurobiology, Harvard Medical School, Boston, United States.ORCID 0000-0002-7294-169X
Corey C HarwellDepartment of Neurobiology, Harvard Medical School, Boston, United States.
Chenghua GuDepartment of Neurobiology, Harvard Medical School, Boston, United States.ORCID 0000-0002-4212-7232
Bernardo L SabatiniHoward Hughes Medical Institute, Department of Neurobiology, Harvard Medical School, Boston, United States.ORCID 0000-0003-0095-9177
Harvard University · USHoward Hughes Medical Institute · US

Funding

Super-Resolution ImagingP30NS072030 · NINDS · HARVARD MEDICAL SCHOOL · PI REGEHR, WADE G · 2011 to 2020
$5.8M
Action and interaction of ionotropic and metabotropic neurotransmissionR37NS046579 · NINDS · HARVARD MEDICAL SCHOOL · PI SABATINI, BERNARDO L · 2018 to 2024
$4.6M
Temporal Specification of Basal Forebrain CircuitryR01MH119156 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HARWELL, COREY C · 2020 to 2023
$1.9M
Temporal Specification of Basal Forebrain CircuitryR56MH119156 · NIMH · HARVARD MEDICAL SCHOOL · PI HARWELL, COREY C · 2019 to 2019
$501k
Synaptic connectivity of Basal Forebrain neurotransmitter systemsK99NS102429 · NINDS · HARVARD MEDICAL SCHOOL · PI GRANGER, ADAM · 2018 to 2019
$179k
NIMH NIH HHS R01 MH119156NIMH NIH HHS R56 MH119156NINDS NIH HHS K99 NS102429NINDS NIH HHS P30 NS072030NINDS NIH HHS R37 NS046579
6 · The paper itself

Abstract

The mouse cerebral cortex contains neurons that express choline acetyltransferase (ChAT) and are a potential local source of acetylcholine. However, the neurotransmitters released by cortical ChAT

Indexed as

AcetylcholineAnimalsBrainCerebral CortexCholine O-Acetyltransferasegamma-Aminobutyric AcidHeterozygoteInterneuronsMiceNeuronsPrefrontal CortexPresynaptic TerminalsAcetylcholineCholine O-Acetyltransferasegamma-Aminobutyric AcidAcetylcholinecortical interneuronsGABAmouseneuromodulationneuroscienceneurotransmitter co-releaseVIP

Identifiers

PMID32613945
PMCPMC7360370
OpenAlexW3038435474

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.