ArticleESC heart failure2020
Left atrial strain as sensitive marker of left ventricular diastolic dysfunction in heart failure.
Article in ESC heart failure, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 77 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
77 citing papers in PubMed, 1 synthesis or guideline pooled it, 94 citations in OpenAlex.
- Heart failure with preserved ejection fraction management: a systematic review of clinical practice guidelines and recommendations.European heart journal. Quality of care & clinical outcomes · 2024Pooled it
- Prognostic significance of left atrial reservoir strain during exercise in patients with heart failure.International journal of cardiology. Heart & vasculature · 2026Article
- Left and Right Atrial Strain Across the Heart Failure Continuum: Multifaceted Markers of Subclinical Mechanical Dysfunction and Haemodynamic Burden.Diagnostics (Basel, Switzerland) · 2026Review
- Left Atrial Strain as an Early Marker of Anthracycline-Related Cardiac Dysfunction (LAS-MACD).Echocardiography (Mount Kisco, N.Y.) · 2026Article
- Strain imaging in heart failure: from early detection to prognostic assessment.ESC heart failure · 2026Review
- Evaluation of myocardial function by strain echocardiography in cats with hypertrophic cardiomyopathy phenotypes.Veterinary world · 2026Article
- Reduced serum Sestrin-1 is associated with subclinical cardiovascular alterations in systemic lupus erythematosus: A controlled cross-sectional study.The Journal of international medical research · 2026Article
- Left atrium strain in rheumatoid arthritis patients - a sub-study of the prospective Porto-RA cohort.Clinical research in cardiology : official journal of the German Cardiac Society · 2026Observational
- Mitral annular plane systolic excursion to left atrial volume ratio as a novel index to assess ventricular filling pressure in dogs with myxomatous mitral valve disease.Veterinary research communications · 2026Article
- Left atrial function in class III obesity: a pilot study using two-dimensional speckle tracking echocardiography.BMC cardiovascular disorders · 2026Observational
- Role of imaging techniques in monitoring atrial cardiomyopathy and atrial failure: a scientific statement.ESC heart failure · 2026Review
- Assessment of left atrial function following patent foramen ovale closure using four-dimensional auto left atrial quantification.BMC cardiovascular disorders · 2026Article
- Artificial intelligence implementation in automated heart chambers quantification during pharmacological stress echocardiography.European heart journal. Digital health · 2026Article
- Comparative analysis of myocardial strain parameters in acute decompensated heart failure phenotypes: a cross-sectional study.Frontiers in cardiovascular medicine · 2026Article
- Left atrial global strain supports left atrial end-diastolic volume as a measure of left atrial function.American heart journal plus : cardiology research and practice · 2025Article
- Left atrial functional remodeling following percutaneous closure of atrial septal defect secundum in adult patients.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2025Article
- Vendor and software based variation in left atrial strain measurements: implications for clinical practice.The international journal of cardiovascular imaging · 2025Article
- Proarrhythmogenic Echocardiographic Markers in Metabolic Syndrome: A Cross-Sectional Study.Life (Basel, Switzerland) · 2025Article
- Integrative speckle-tracking echocardiography for the early detection and prediction of cancer therapy-related cardiac dysfunction.Cardio-oncology (London, England) · 2025Article
- Diastolic Function and Left Atrial Mechanics in Children With Marfan and Loeys-Dietz Syndrome.CJC pediatric and congenital heart disease · 2025Article
17 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
12 authors at 7 institutions in 4 countries.
Funding
Abstract
aimsThe purpose of this retrospective analysis was to examine the association of left atrial (LA) strain (i.e. LA reservoir function) with left ventricular diastolic dysfunction (DD) in patients with heart failure with reduced and preserved left ventricular ejection fraction (LVEF). METHODS AND
resultsWe analysed the baseline echocardiographic recordings of 300 patients in sinus rhythm from the SOCRATES-PRESERVED and SOCRATES-REDUCED studies. LA volume index was normal in 89 (29.7%), of whom 60.6% had an abnormal LA reservoir strain (i.e. ≤23%). In addition, the extent of LA strain impairment was significantly associated with the severity of DD according to the 2016 American Society of Echocardiography recommendations (DD grade I: LA strain 22.2 ± 6.6, rate of abnormal LA strain 62.9%; DD grade II: LA strain 16.6 ± 7.4, rate of abnormal LA strain 88.6%; DD grade III: LA strain 11.1 ± 5.4%, rate of abnormal LA strain 95.7%; all P < 0.01). In line with these findings, LA strain had a good diagnostic performance to determine severe DD [area under the curve 0.83 (95% CI 0.77-0.88), cut-off 14.1%, sensitivity 80%, specificity 77.8%], which was significantly better than for LA volume index, LA total emptying fraction, and the mitral E/e' ratio.
conclusionsThe findings of this analysis suggest that LA strain could be a useful parameter in the evaluation of DD in patients with heart failure and sinus rhythm, irrespective of LVEF.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.